| Identification | Back Directory | [Name]
Dexamethasone cipecilate | [CAS]
132245-57-9 | [Synonyms]
NS 126
Dexamethasone cipecilate
Pregna-1,4-diene-3,20-dione, 21-[(cyclohexylcarbonyl)oxy]-17-[(cyclopropylcarbonyl)oxy]-9-fluoro-11-hydroxy-16-methyl-, (11β,16α)- | [Molecular Formula]
C33H43FO7 | [MOL File]
132245-57-9.mol | [Molecular Weight]
570.69 |
| Hazard Information | Back Directory | [Uses]
Dexamethasone cipecilate (NS-126) is a corticosteroid whose local efficacy and durability have been enhanced by the introduction of a lipophilic functional group. Dexamethasone cipecilate can be used as a nasal spray and is applicable in rhinitis research[1]. | [Definition]
ChEBI: [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-17-(cyclopropanecarbonyloxy)-9-luoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] cyclohexanecarboxylate is a corticosteroid hormone. | [References]
[1] Gotoh M, et al. Clinical pharmacology study of the corticosteroid nasal spray dexamethasone cipecilate (NS-126): examination of the durability of efficacy in the nasal induction test. Expert Opin Investig Drugs. 2010 Dec;19(12):1475-86. DOI:10.1517/13543784.2010.531258 |
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