| Identification | Back Directory | [Name]
NEOERIOCITRIN | [CAS]
13241-32-2 | [Synonyms]
C09805
NEOERIOCITRIN
NEOERIOCITRIN WITH HPLC
ERIODICTYOL-7-NEOHESPERIDOSIDE
ERIODICTYOL-7-O-NEOHESPERIDOSIDE
Neoeriocitrin, froM Citrus nobilis
ERIODICTYOL-7-NEOHESPERIDOSIDE hplc
(s)-3',4',5,7-tetrahydroxyflavanone-7-[2-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside]
(S)-3',4',5,7-TETRAHYDROXYFLAVANONE-7-[2-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]
(S)-7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one,7-[[2-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-,(2S)-
4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-, (2S)-
(S)-7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-benzopyran-4-one
7-[[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxy-6-methyl-2-oxanyl)oxy]-2-oxanyl]oxy]-2-(3,4-dihydroxyphenyl)-5-hydroxy-3,4-dihydro-2H-1-benzopyran-4-one | [EINECS(EC#)]
236-215-3 | [Molecular Formula]
C27H32O15 | [MDL Number]
MFCD00017474 | [MOL File]
13241-32-2.mol | [Molecular Weight]
596.53 |
| Chemical Properties | Back Directory | [Melting point ]
277°C | [Boiling point ]
960.7±65.0 °C(Predicted) | [density ]
1.73±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in methanol; | [form ]
powder | [pka]
7.14±0.40(Predicted) | [color ]
White | [Water Solubility ]
insoluble in water | [BRN ]
1696764 | [InChIKey]
OBKKEZLIABHSGY-DOYQYKRZSA-N | [SMILES]
C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O | [LogP]
2.130 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Off white powder | [Uses]
Neoeriocitrin, isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor[1][2]. | [Definition]
ChEBI: A flavanone glycoside that is eriodictyol substituted by a 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. | [Biological Activity]
Neoeriocitrin was one of several flavonoids th at completely blocked the okadaic acid-induced inhibition of autophagy in cultured mouse hepatocytes. It is suggested as tool in the study of intracellular protein phosphorylation and as a potential protectant against pathological hyperphosphorylations. | [IC 50]
AChE | [References]
[1] Li L, et al. Comparison of?neoeriocitrin?and naringin on proliferation and osteogenic differentiation in MC3T3-E1. Phytomedicine.?2011 Aug 15;18(11):985-9. DOI:10.1016/j.phymed.2011.03.002
[2] Liu C, et al. Extraction and Isolation of Acetylcholinesterase Inhibitors from Citrus limon Peel Using an in vitro Method. J Sep Sci.?2020 Jan 30. DOI:10.1002/jssc.201901252 |
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