| Identification | More | [Name]
4-CHLORO-2,5-DIFLUOROBENZOIC ACID | [CAS]
132794-07-1 | [Synonyms]
2,5-DIFLUORO-4-CHLOROBENZOIC ACID
4-CHLORO-2,5-DIFLUOROBENZOIC ACID
TIMTEC-BB SBB003617
2,5-Difluoro-4-chlorobenzoic
4-Chloro-2,5-difluorobenzoic acid 98%
4-Chloro-2,5-difluorobenzoicacid98% | [Molecular Formula]
C7H3ClF2O2 | [MDL Number]
MFCD00077480 | [Molecular Weight]
192.55 | [MOL File]
132794-07-1.mol |
| Chemical Properties | Back Directory | [Appearance]
OFF-WHITE CRYSTALLINE POWDER | [Melting point ]
154-157 °C (lit.) | [Boiling point ]
258°C (rough estimate) | [density ]
1.4821 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Crystalline Powder | [pka]
2.70±0.10(Predicted) | [color ]
Off-white | [InChI]
InChI=1S/C7H3ClF2O2/c8-4-2-5(9)3(7(11)12)1-6(4)10/h1-2H,(H,11,12) | [InChIKey]
PEPCYJSDHYMIFN-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC(F)=C(Cl)C=C1F | [CAS DataBase Reference]
132794-07-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302+H312+H332-H315-H319-H335 | [Precautionary statements ]
P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29163990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
OFF-WHITE CRYSTALLINE POWDER | [Uses]
4-Chloro-2,5-difluorobenzoic acid reacts with substituted 2-hydroxy acetophenones in the presence of POCl3 to afford 2-acetylphenyl-4-chloro-2,5-difluorobenzoate. | [General Description]
4-Chloro-2,5-difluorobenzoic acid reacts with substituted 2-hydroxy acetophenones in the presence of POCl3 to afford 2-acetylphenyl-4-chloro-2,5-difluorobenzoate. |
| Questions And Answer | Back Directory | [Application]
4-Chloro-2,5-difluorobenzoic acid is a pharmaceutical intermediate that can be used to synthesize drugs that promote insulin secretion and inhibit the increase of blood glucose concentration. It can also be used to synthesize intermediates for protein kinase inhibitors and an isothiazole derivative, which is an intermediate for an anticancer drug. |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 18918157536; |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Adamas Reagent, Ltd.
|
| Telephone: |
4006009262 13023226327 |
| Website: |
http://www.tansoole.com |
|