ChemicalBook--->CAS DataBase List--->134-35-0

134-35-0

134-35-0 Structure

134-35-0 Structure
IdentificationBack Directory
[Name]

METHYL FOLATE(METAFOLIN)(P)
[CAS]

134-35-0
[Synonyms]

n5-CH3-THF
methyl-H4F
methyl-THF
Prefolic A
5-METHYL-THF
MethylFolate
N5-methyl-THF
L-Methyl Folate
N-Methyltetrahydrofolate
5-methyltetrahydrofolate
METHYLTETRAHYDROFOLICACID
n5-methyltetrahydrofolate
METHYL FOLATE(METAFOLIN)(P)
N-Methyltetrahydrofolic acid
N5-Methyl tetrahydrofolic acid
5-methyl-5,6,7,8-tetrahydrofolate
N5-Methyltetrahydropteroylglutamate
5-Methyl-5,6,7,8-tetrahydrofolic acid
5-Methyltetrahydropteroylglutamic acid
5-Methyltetrahydropteroyl monoglutamate
N5-methyltetrahydropteroyl mono-L-glutamate
5-methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Methyltetrahydrofolic Acid CalciuM Salt Trihydrate
5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate (Also See: L375720)
5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate (Mixture of Diastereomers)
N-[4-[[(2-Amino-1,4-dihydro-4-oxopteridin)-6-ylmethyl]amino]benzoyl]-L-glutamic acid 5-methyl ester
2-[4-[(2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid
(2S)-2-(4-(((2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
N-[4-[[(2-AMino-3,4,5,6,7,8-hexahydro-5-Methyl-4-oxo-6-pteridinyl)Methyl]aMino]benzoyl]-L-glutaMic Acid CalciuM Trihydrate
[EINECS(EC#)]

1592732-453-0
[Molecular Formula]

C20H20N7O6-
[MDL Number]

MFCD00900533
[MOL File]

134-35-0.mol
[Molecular Weight]

454.416
Chemical PropertiesBack Directory
[Melting point ]

>300°C (dec.)
[density ]

1.62±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer, Under Inert Atmosphere
[solubility ]

Aqueous Base (Slightly, Sonicated)
[form ]

Solid
[pka]

3.51±0.10(Predicted)
[color ]

Pale Beige
[Stability:]

Hygroscopic
[InChIKey]

ZNOVTXRBGFNYRX-ABLWVSNPSA-N
[SMILES]

C(O)(=O)[C@H](CCC(O)=O)NC(=O)C1=CC=C(NCC2CNC3=C(N2C)C(=O)NC(N)=N3)C=C1
Questions And AnswerBack Directory
[Description]

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.
[Supplements]

5-Methyltetrahydrofolic acid is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.
[Mechanism of Action]

Prefolic A, also known as 5-Methyltetrahydrofolate, is a biologically active form of folic acid that functions, in conjunction with vitamin B12, as a methyl-group donor involved in the conversion of homocysteine to methionine. Methyl folate is an active metabolite of folic acid. Vitamin supplement in health care products.
[Shipping & Storage Condition]

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Stored in dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Shelf Life can be more than 2 years if stored properly.
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

A metabolite of Folic acid; inhibits photosensitization reactions and strand breaks in DNA
[General Description]

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group.
5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.
[IC 50]

Human Endogenous Metabolite
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
[REACH Registrations]

Active
Spectrum DetailBack Directory
[Spectrum Detail]

5-Methyltetrahydrofolic acid(134-35-0)1HNMR
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