| Identification | Back Directory | [Name]
11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE | [CAS]
134179-38-7 | [Synonyms]
N3-PEG3-NH2
Amino-PEG4-Azide
Amino-PEG3-azide
Azido-PEG3-amine
N3-PEG3-CH2CH2NH2
11-Azido-3,6,9-trioxaundecylamine
1-Amino-11-azido-3,6,9-trioxaundecane
11-Azido-3,6,9-trioxaundecane-1-amine
1-[2-(2-Aminoethoxy)ethoxy]-2-(2-azidoethoxy)ethane
11-Azido-3,6,9-trioxaundecan-1-aMine technical, >=90% (GC)
1-Amino-11-azido-3,6,9-trioxaundecane
11-Amino-3,6,9-trioxaundecanyl Azide
2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethylamine, 1-Amino-11-azido-3,6,9-trioxaundecane
1-Amino-11-azido-3,6,9-trioxaundecane, 2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethylamine, O-(2-Aminoethyl)-Oμ-(2-azidoethyl)diethylene glycol | [Molecular Formula]
C8H18N4O3 | [MDL Number]
MFCD00269874 | [MOL File]
134179-38-7.mol | [Molecular Weight]
218.25 |
| Chemical Properties | Back Directory | [Appearance]
Very Pale Yellow Oil | [Boiling point ]
198-202°C | [density ]
1.10 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.470
| [storage temp. ]
Amber Vial, Refrigerator, Under Inert Atmosphere | [solubility ]
miscible with water, polar organic solvents | [form ]
Viscous Liquid | [color ]
Yellow to Pale Brown | [BRN ]
4745506 | [Stability:]
Light Sensitive | [InChI]
InChI=1S/C8H18N4O3/c9-1-3-13-5-7-15-8-6-14-4-2-11-12-10/h1-9H2 | [InChIKey]
FPVCVHVTMPCZTH-UHFFFAOYSA-N | [SMILES]
C(OCCOCCN)COCCN=[N+]=[N-] |
| Hazard Information | Back Directory | [Chemical Properties]
Very Pale Yellow Oil | [Uses]
A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules.
PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins. | [Description]
Amino-PEG3-azide is a bifunctional PEG linker containing an amino group and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. | [reaction suitability]
reaction type: click chemistry
reagent type: cross-linking reagent | [Synthesis]
In a dry reactor, hydrazine monohydrate (0.95 mL, 19.5 mmol) was added to a solution of TEG-azide (1.7 g, 4.9 mmol) dissolved in (40 mL) under a nitrogen atmosphere. The reaction mixture was then heated and stirred under reflux for 18 hours. At the e |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|