| Identification | Back Directory | [Name]
5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester | [CAS]
756526-02-0 | [Synonyms]
Fmoc-NH-PEG8-OH
Fmoc-NH-PEG8-COOH
Fmoc-PEG8-CH2CH2COOH
Fmoc-N-amido-PEG8-acid
FMoc-NH-PEG8-CH2CH2COOH
Fmoc-NH-PEG28-CH2CH2COOH
Fmoc-PEG8-propionic acid
Fmoc-N-amido-dPEG 8-acid
FMOC-AMINO-PEG8-PROPANOIC ACID
3-Fmoc-Amino(peg8)propionic acid
5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid
Fmoc-NH-(PEG)8-CH2CH2COOH
1-(Fmoc-amino)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic Acid
5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester
5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(9H-fluoren-9-ylMethyl) ester
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azahentriacontan-31-oic acid
Fmoc-PEG8-OH
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azahentriacontan-31-oic acid | [EINECS(EC#)]
246-818-3 | [Molecular Formula]
C34H49NO12 | [MDL Number]
MFCD11041143 | [MOL File]
756526-02-0.mol | [Molecular Weight]
663.75 |
| Chemical Properties | Back Directory | [Boiling point ]
781.1±60.0 °C(Predicted) | [density ]
1.190±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [form ]
liquid | [pka]
4.28±0.10(Predicted) | [color ]
Colorless to light yellow | [InChIKey]
VYXGUCLTEWCVRY-UHFFFAOYSA-N | [SMILES]
C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O |
| Hazard Information | Back Directory | [Description]
Fmoc-N-amido-PEG8-acid (CAS: 756526-02-0) is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
| [Uses]
Fmoc-NH-PEG8-CH2CH2COOH is used in synthesis of protein-antiviral compound conjugates. | [General Description]
Fmoc-NH-PEG8-CH₂CH₂COOH (CAS 756526-02-0) is a high-purity, degradable ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). Its synonyms include Fmoc-N-amido-PEG8-acid, Fmoc-NH-PEG8-COOH, Fmoc-PEG8-propionic acid and Fmoc-NH-PEG8-propionic acid, amongst others. | [reaction suitability]
reaction type: Pegylations | [IC 50]
Cleavable Linker; PEGs |
|
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
T&W GROUP
|
| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
|