| Identification | Back Directory | [Name]
PITUITARY ADENYLATE CYCLASE ACTIVATING | [CAS]
136134-68-4 | [Synonyms]
pacap-6-27
Human PACAP(6-27)
Pacap (6-27)-human
PITUITARY ADENYLATE CYCLASE ACTIVATING
pituitary adenylate cyclase activating polypeptide amide fragment 6-27
Pituitary Adenylate Cyclase Activating Polypeptide-27 (6-27) (huMan, chicken, Mouse, ovine, porcine, rat)
L-Leucinamide, L-phenylalanyl-L-threonyl-L-α-aspartyl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-tyrosyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alanyl-L-alanyl-L-valyl- | [Molecular Formula]
C121H193N33O31S | [MDL Number]
MFCD00145059 | [MOL File]
136134-68-4.mol | [Molecular Weight]
2638.09 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [form ]
Solid | [color ]
White to off-white | [Sequence]
Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2 |
| Hazard Information | Back Directory | [Uses]
PACAP (6-27) (human, ovine, rat) is a PACAP receptor antagonist that blocks the canine adrenal catecholamine response to exogenous vasoactive intestinal peptide (VIP). PACAP (6-27) (human, ovine, rat) has the potential to study cardiovascular and neurological diseases[1]. | [References]
[1] Gaspo R, et al. Canine adrenal catecholamine response to VIP is blocked by PACAP-(6-27) in vivo. Am J Physiol. 1997 May;272(5 Pt 2):R1606-12. DOI:10.1152/ajpregu.1997.272.5.R1606 |
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