| Identification | Back Directory | [Name]
N-(4'-Cyano[1,1'-biphenyl]-4-yl)-N'-[4-(3H-iMidazo[4,5-b]pyridin-7-yl)phenyl] Urea | [CAS]
1361414-26-7 | [Synonyms]
ML368
ML-368
ML 368
SR 9186
1-(4-(3H-Imidazo[4,5-b]pyridin-7-yl)phenyl)-3-(4'-cyano-[1,1'-biphenyl]-4-yl)urea
N-(4'-Cyano[1,1'-biphenyl]-4-yl)-N'-[4-(3H-iMidazo[4,5-b]pyridin-7-yl)phenyl] Urea
SR 9186 1-[4-(4-Cyanophenyl)phenyl]-3-[4-(1H-imidazo[4,5-b]pyridin-7-yl)phenyl]urea | [Molecular Formula]
C26H18N6O | [MDL Number]
MFCD28160686 | [MOL File]
1361414-26-7.mol | [Molecular Weight]
430.461 |
| Chemical Properties | Back Directory | [Melting point ]
>300°C | [Boiling point ]
676.2±55.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
DMF, DMSO (Slightly) | [form ]
Solid | [pka]
9.91±0.40(Predicted) | [color ]
Pale Yellow |
| Hazard Information | Back Directory | [Uses]
N-(4'-Cyano[1,1'-biphenyl]-4-yl)-N'-[4-(3H-imidazo[4,5-b]pyridin-7-yl)phenyl] Urea, is a highly selective inhibitor of cytochrome P450 3A4, which is one of the most important enzymes involved in the metabolism of pharmaceuticals and xenobiotics. | [Uses]
N-(4''-Cyano[1,1''-biphenyl]-4-yl)-N''-[4-(3H-imidazo[4,5-b]pyridin-7-yl)phenyl] Urea, is a highly selective inhibitor of cytochrome P450 3A4, which is one of the most important enzymes involved in the metabolism of pharmaceuticals and xenobiotics. | [IC 50]
Plasmodium; CYP3 |
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BOC Sciences
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www.bocsci.com |
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Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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