| Identification | More | [Name]
2-FLUORO-4-IODOBENZONITRILE | [CAS]
137553-42-5 | [Synonyms]
2-FLUORO-4-IODOBENZONITRILE
2-Fluoro-4-iodobenzonitrile 98%
2-Fluoro-4-iodobenzonitrile98%
4-Iodo-2-fluorobenzonitrile | [EINECS(EC#)]
604-024-8 | [Molecular Formula]
C7H3FIN | [MDL Number]
MFCD03094172 | [Molecular Weight]
247.01 | [MOL File]
137553-42-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
103.7-104.6 | [Boiling point ]
264.0±25.0 °C(Predicted) | [density ]
1.98±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml | [form ]
Powder | [color ]
Red-brown | [Water Solubility ]
Slightly soluble in water. | [Sensitive ]
Light Sensitive | [CAS DataBase Reference]
137553-42-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi | [RIDADR ]
UN3439 | [Hazard Note ]
Toxic | [HazardClass ]
6.1 | [HazardClass ]
IRRITANT, IRRITANT-HARMFUL | [HS Code ]
2926907090 |
| Hazard Information | Back Directory | [Description]
2-Fluoro-4-iodo benzonitrile is a building block.1,2 It has been used in the synthesis of L. infantum trypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors.1 2-Fluoro-4-iodo benzonitrile has also been used in the synthesis of transient receptor potential ankyrin 1 (TRPA1) antagonists.2 | [Chemical Properties]
Light yellow crystalline | [Uses]
Used as pharmaceutical intermediates. | [References]
[1] ALEJANDRO REVUELTO. Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase[J]. ACS Infectious Diseases, 2019, 5 6: 873-891. DOI: 10.1021/acsinfecdis.8b00355
[2] KARL S.A. VALLIN . N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor[J]. Bioorganic & Medicinal Chemistry Letters, 2012, 22 17: Pages 5485-5492. DOI: 10.1016/j.bmcl.2012.07.032 |
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| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
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