ChemicalBook--->CAS DataBase List--->946578-00-3

946578-00-3

946578-00-3 Structure

946578-00-3 Structure
IdentificationBack Directory
[Name]

Sulfoxaflor
[CAS]

946578-00-3
[Synonyms]

GF 2032
GF 2372
XDE 208
13c,98%)
Sulfoxaflo
-SULFANONE
Sulfoxaflor
Transform 50 WG
Sulfoxaflor 50%WDG
Sulfoxaflor solution
Sulfoxaflor 95%, 50%WDG
Sulfoxaflor cas 946578-00-3
Sulfoxaflor solution,1000ppm
Transfarmer (Sulfoxaflor) 50 WG
Sulfoxaflor(mixture of isomers)
Sulfoxaflor@100 μg/mL in Methanol
Transform 50 WG (Sulfoxaflor 50%WDG)
Sulfoxaflor@1000 μg/mL in Acetonitrile
Transform WG New Insecticide Label for Cotton
[methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lam...
(CYANOIMINO)(METHYL){1-[6-(TRIFLUOROMETHYL)PYRIDIN-3-YL]ETHYL}-Λ⁶
(cyanoimino)(methyl){1-[6-(trifluoromethyl)pyridin -3-yl]ethyl}-lambda6-sulfanone
Cyanamide,N-[methyloxido[1-[6-(trifluoromethyl)-3-pyridinyl]ethyl]-l4-sulfanylidene]-
Cyanamide, N-[methyloxido[1-[6-(trifluoromethyl)-3-pyridinyl]ethyl]-λ4-sulfanylidene]-
[methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda~4~-sulfanylidene]cyanamide
Sulfoximine,Inhibitor,median,unpaired,insecticide,dorsal,nAChR1,Sulfoxaflor,nAChR2,Nicotinic acetylcholine receptors,inhibit,nAChR
[EINECS(EC#)]

202-303-5
[Molecular Formula]

C10H10F3N3OS
[MDL Number]

MFCD22572331
[MOL File]

946578-00-3.mol
[Molecular Weight]

277.27
Chemical PropertiesBack Directory
[Boiling point ]

363.8±52.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[solubility ]

Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
[InChI]

InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3
[InChIKey]

ZVQOOHYFBIDMTQ-UHFFFAOYSA-N
[SMILES]

C(C1=CN=C(C(F)(F)F)C=C1)(C)S(=O)(C)=NC#N
[LogP]

1.259 (est)
[EPA Substance Registry System]

Cyanamide, N-[methyloxido[1-[6-(trifluoromethyl)-3-pyridinyl]ethyl]-.lamda.4-sulfanylidene]- (946578-00-3)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
[Signal word ]

Warning
[Hazard statements ]

H302-H410
[Precautionary statements ]

P264-P270-P301+P312-P330-P501-P273-P391-P501
[Hazardous Substances Data]

946578-00-3(Hazardous Substances Data)
Hazard InformationBack Directory
[Description]

Sulfoxaflor is an insecticide that is used to control aphids in field crops and favourably compares with imidacloprid in efficiacy. It is relatively volatile, whilst potentially mobile in soils it has a low potential for leaching due to its rapid degradation rate. It has a high potential to bioaccumulate, generally moderately toxic to birds and mammals and has a low toxicity to most aquatic species. It is toxic to honeybees and earthworms
[History]

lt was first registered by EPA for emergency use on cotton to controltarnished plant bug, Lygus lineolaris in the state of Mississippi,Arkansas,Louisiana, and Tennessee in June 2012. lts use was extended to other cropsin 2013.Sulfoxaflor is registered for use in Minnesota in June 2013. 
[Uses]

Sulfoxaflor-d3 is the isotope analog of Sulfoxaflor. Sulfoxaflor, is a new insecticide which acts as an insect neurotoxin, and is the only member of class of chemicals called the sulfoximines which act on the central nervous system of insects with much lower toxicity to mammals.
[Definition]

ChEBI: [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide is a member of the class of pyridines that is 5-ethyl-2-trifluoromethylpyridine in which the ethyl group is substituted at position 1 by an N-cyano-S-methylsulfonimidoyl group. The insecticide sulfoxalor is a mixture of the four possible stereoisomers arising from the two tetrahedral stereocentres. It is a member of pyridines, a sulfoximide, a nitrile and an organofluorine compound.
[Production Methods]

Sulfoxaflor is commercially produced via a multi-step process starting with the nucleophilic addition of methyl mercaptan to cyanogen chloride to form [[(methylthio)methyl]thio]acetonitrile, which is oxidised with hydrogen peroxide under acidic conditions to the corresponding sulfoximine; this intermediate undergoes cyclisation with ethyl acetoacetate and subsequent amination with 2-chloro-5-(trifluoromethyl)pyridine to yield the active compound.
[benefits]

Sulfoxaflor may be registered for use on the following major crops inMinnesota: soybeans, potatoes, wheat. According to UMN extension,sulfoxaflor worked well against aphids in soybean and potatoes. It will beof use against piercing/sucking insects such as aphids, leafhoppers, plantbugs, etc. lt is not labeled for residential uses.
[Mechanism of action]

Systemic. Nicotinic acetylcholine receptor (nAChR) channel blocker.
[Toxicology]

EPA's screening models generote high-end, conservative exposure estimates for active ingredients and toxicologically significant degrodates. Model inputs include annual usage ot moximum use rates, maximum treated acres, maximum food residues, peak runoffand drift scenarios, etc. Ssome proposed products, application rates and use scenarios are not relevant to Minnesota.EPA's estimates,therefore, may not reflect future use and impacts in Minnesota.
[Environmental Fate]

The fate of sulfoxoflor in the environment is highly dependent on whether it is in a soil ystem, groundwater system, or surface watersystem. Environmental fate characteristics are listed for parent and all relevant degradates where appropriate.
[Pesticide Type]

Insecticide
Spectrum DetailBack Directory
[Spectrum Detail]

Sulfoxaflor(946578-00-3)1HNMR
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