| Identification | More | [Name]
Nalpha-Fmoc-L-lysine hydrochloride | [CAS]
139262-23-0 | [Synonyms]
FMOC-L-LYSINE HYDROCHLORIDE
FMOC-LYSINE HCL
FMOC-LYS-OH HCL
Fmoc-Lys-OH hydrochloride
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-LYSINE HYDROCHLORIDE
N-ALPHA-FMOC-L-LYSINE, HCL
N(ALPHA)-FMOC-L-LYSINE HYDROCHLORIDE
Nα-Fmoc-L-lysine hydrochloride
nα-fmoc-l-lysine hydrochloride
Fmoc-L-Lys-OH·HCl
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine Hydrochloride | [Molecular Formula]
C21H25ClN2O4 | [MDL Number]
MFCD00190889 | [Molecular Weight]
404.89 | [MOL File]
139262-23-0.mol |
| Chemical Properties | Back Directory | [refractive index ]
-11.0 ° (C=1, DMF) | [storage temp. ]
2-8°C
| [solubility ]
Soluble in dimethyl formamide (0.3g in 2ml). | [form ]
powder to crystal | [color ]
White to Almost white | [BRN ]
8663370 | [InChIKey]
MVMZFAIUUXYFGY-FYZYNONXSA-N | [SMILES]
C(C1C2=CC=CC=C2C2C=CC=CC1=2)OC(=O)N[C@H](C(=O)O)CCCCN.Cl |&1:18,r| | [CAS DataBase Reference]
139262-23-0(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used to synthesize antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also an alkyl chain-based PROTAC linker that can be used to synthesize PROTACs.
| [Chemical Properties]
White solid | [Uses]
It is used as an active pharmaceutical intermediate and in the synthesis of nε-(7-diethylaminocoumarin-3-carboxyl)- and nε-(7-methoxycoumarin-3-carboxyl)-l-fmoc lysine as tools for protease cleavage detection by fluorescence. | [reaction suitability]
reaction type: Fmoc solid-phase peptide synthesis | [IC 50]
Non-cleavable Linker |
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