| Identification | Back Directory | [Name]
4-O-(Carboxymethyl)rifamycin | [CAS]
13929-35-6 | [Synonyms]
C01848
Nacimycin
Nancimycin
NCI-145-604
Rifomycin B
Rifamycin B CRS
Rifamycin impurity A
Rifaximin EP Impurity B
Rifamycin EP Impurity A
Rifaximin impurity B (EP)
4-O-(Carboxymethyl)rifamycin
Rifamycin, 4-O-(carboxymethyl)-
Rifaximin EP Impurity B (Rifamycin B)
Rifaximin Impurity 2 (Rifaximin EP Impurity B)
Rifamycin Impurity 1(Rifamycin EP Impurity A)（Rifamycin B) | [EINECS(EC#)]
237-697-8 | [Molecular Formula]
C39H49NO14 | [MOL File]
13929-35-6.mol | [Molecular Weight]
755.8 |
| Chemical Properties | Back Directory | [Melting point ]
300° (dec 160-164°) | [alpha ]
D20 -11° (methanol) | [Boiling point ]
730.16°C (rough estimate) | [density ]
1.2421 (rough estimate) | [refractive index ]
1.5350 (estimate) | [form ]
neat | [pka]
2.69±0.10(Predicted) | [BRN ]
604953 |
| Hazard Information | Back Directory | [Uses]
A Rifamycin (R508200) derivative as antibacterial agent. | [Uses]
Rifamycin B (Rifaximin EP Impurity B) is a Rifamycin (R508200) derivative as antibacterial agent. | [Definition]
ChEBI: Rifamycin B is a carboxylic acid, an acetate ester, an organic heterotetracyclic compound and a member of rifamycins. It is a conjugate acid of a rifamycin B(2-). | [Purification Methods]
Rifamycin B forms yellow needles from *C6H6. Its solubilities are: H2O (0,027%), MeOH (2.62%) and EtOH (0.44%). It has UV max at 223, 304 and 245nm (A 1cm 555, 275 and 220). [Oppolzer & Prelog Helv Chim Acta 56 2287 1973, Oppolzer et al. Experientia 20 336 1964, X-ray: Brufani et al. Experientia 20 339 1964.] |
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