ChemicalBook--->CAS DataBase List--->571-60-8

571-60-8

571-60-8 Structure

571-60-8 Structure
IdentificationMore
[Name]

1,4-Dihydroxynaphthalene
[CAS]

571-60-8
[Synonyms]

1,4-DIHYDROXYNAPHTHALENE
1,4-NAPHTHALENEDIOL
1,4-NAPHTHOHYDROQUINONE
1,4-NAPTHALENEDIOL
1,4-NDO
ALPHA-NAPHTHOHYDROQUINONE
NAPHTHALENE-1,4-DIOL
P-NAPHTHOHYDROQUINONE
1,4-dihydroxynaphthalene,1:1mixturewith1,4-naphthoquinone
1,4-naphthoquinol
1,4-Naphththalenediol
alpha-naphthoquinhydrone
Hydronaphthoquinone
Naphthalenediol-(1,4)
Naphthohydroquinone
1,4-Dihydroxynaphthalene, 95+%
1,4-DIHYDROXYNAPTHALENE
1,4-Naphthalenediol, p-Naphthohydroquinone (α)
[EINECS(EC#)]

209-336-4
[Molecular Formula]

C10H8O2
[MDL Number]

MFCD00003977
[Molecular Weight]

160.17
[MOL File]

571-60-8.mol
Chemical PropertiesBack Directory
[Appearance]

brown to greyish powder
[Melting point ]

191-192 °C (dec.)
[Boiling point ]

246.06°C (rough estimate)
[density ]

1.0924 (rough estimate)
[refractive index ]

1.5178 (estimate)
[storage temp. ]

Refrigerator
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

neat
[pka]

pK1:9.37;pK2:10.93 (26°C,μ=0.65)
[color ]

Grey
[Water Solubility ]

slightly soluble
[BRN ]

1307689
[InChI]

1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H
[InChIKey]

PCILLCXFKWDRMK-UHFFFAOYSA-N
[SMILES]

Oc1ccc(O)c2ccccc12
[CAS DataBase Reference]

571-60-8(CAS DataBase Reference)
[NIST Chemistry Reference]

1,4-Naphthalenediol(571-60-8)
[EPA Substance Registry System]

571-60-8(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xn,T
[Risk Statements ]

R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R43:May cause sensitization by skin contact.
R36/37/38:Irritating to eyes, respiratory system and skin .
R25:Toxic if swallowed.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S24:Avoid contact with skin .
[WGK Germany ]

3
[RTECS ]

QJ4730000
[F ]

8-10-16-23
[TSCA ]

TSCA listed
[HS Code ]

2921450090
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Aquatic Chronic 3
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

1,4-Dihydroxynaphthalene(571-60-8).msds
Hazard InformationBack Directory
[Chemical Properties]

brown to greyish powder
[Uses]

1,4-Dihydroxynaphthalene is frequently used in organic synthesis as a reagent. In particular, it is used in the synthesis of a pH independent and cell permeant fluorescent dye, a hydroxyl regioisomeric 3'',4''-benzorhodol, which can be used as a fluorescent chemosensor and biomarker for biological applications.
[Definition]

ChEBI: Naphthalene-1,4-diol is a naphthalenediol and a naphthohydroquinone.
[Biological Activity]

1,4-Dihydroxynaphthalene is a potent HSV-1 protease inhibitor with inhibitory effects on the HCMV protease, which can be used to study herpesviruses.
[References]

[1] LAURIE S. TSURUDA   A. D J  Michael W Lamé. Formation of epoxide and quinone protein adducts in B6C3F1 mice treated with naphthalene, sulfate conjugate of 1,4-dihydroxynaphthalene and 1,4-naphthoquinone[J]. Archives of Toxicology, 1995, 69 6: 362-367. DOI:10.1007/s002040050185.
Spectrum DetailBack Directory
[Spectrum Detail]

1,4-Dihydroxynaphthalene(571-60-8)MS
1,4-Dihydroxynaphthalene(571-60-8)1HNMR
1,4-Dihydroxynaphthalene(571-60-8)13CNMR
1,4-Dihydroxynaphthalene(571-60-8)IR1
1,4-Dihydroxynaphthalene(571-60-8)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

1,4-Dihydroxynaphthalene, 1:1 mixture with 1,4-naphthoquinone(571-60-8)
[Sigma Aldrich]

571-60-8(sigmaaldrich)
[TCI AMERICA]

1,4-Dihydroxynaphthalene,>95.0%(GC)(T)(571-60-8)
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