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140187-23-1

140187-23-1 Structure

140187-23-1 Structure
IdentificationBack Directory
[Name]

(S)-(-)-5-FLUOROWILLARDIINE
[CAS]

140187-23-1
[Synonyms]

5-fluorowillardiine
(S)-(-)-5-FLUOROWILLARDIINE
3-(5-fluorouracil-1-yl)-L-alanine
(S)-(-)-5-FLUOROWILLARDIINE USP/EP/BP
WILLARDIINE, S(-)-5-FLUORO POTENT AMPA/K AINATE A
(S)-(-)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)pyridinepropanoicacid
(αS)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
(S)-(-)-ALPHA-AMINO-5-FLUORO-3,4-DIHYDRO-2,4-DIOXO-1(2H)PYRIDINEPROPANOIC ACID
(S)-2-amino-3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid
1(2H)-Pyrimidinepropanoic acid, α-amino-5-fluoro-3,4-dihydro-2,4-dioxo-, (αS)-
(S)-(-)-alpha-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimmidinepropanoic acid
[Molecular Formula]

C7H8FN3O4
[MDL Number]

MFCD00153880
[MOL File]

140187-23-1.mol
[Molecular Weight]

217.15
Chemical PropertiesBack Directory
[storage temp. ]

Sealed in dry,Room Temperature
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictograms
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Definition]

ChEBI: An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively).
[Biological Activity]

A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (K i = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). Also available as part of the AMPA Receptor Tocriset™ .
Spectrum DetailBack Directory
[Spectrum Detail]

(S)-(-)-5-FLUOROWILLARDIINE(140187-23-1)1HNMR
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