ChemicalBook--->CAS DataBase List--->9000-86-6

9000-86-6

9000-86-6 Structure

9000-86-6 Structure
IdentificationBack Directory
[Name]

EC 2.6.1.2
[CAS]

9000-86-6
[Synonyms]

GPT
AAT1
ALT1
GPT1
GPT/ALT
GPT, HUMAN
EC 2.6.1.2
TRANSAMINASE
EC 2.6.1.2 USP/EP/BP
ALANINE AMINOTRANSFERASE
Aminotransferase, alanine
L-ALANINE AMINOTRANSFERASE
GLUTAMIC-PYRUVIC TRANSAMINASE
glutamate-pyruvic transaminase
GLUTAMATE-PYRUVATE TRANSAMINASE
Alanine-pyruvate aminotransferase
Glutamic-Pyruvic Transaminase(GPT)
ANTI-GPT antibody produced in mouse
Glutamic Pyruvic Transaminase (ALT)
Transaminase, broad-range bacterial
Native Human Alanine Aminotransferase
Alanine-oxaloacetate aminotransferase
GLUTAMATE PYRUVATE TRANSAMINASE, HUMAN
Native E. coli Alanine Aminotransferase
95675, ALANINE AMINOTRANSFERASE (CATALYT
L-ALANINE: 2-OXOGLUTARATE AMINOTRANSFERASE
Alanine-alpha-ketoglutarate aminotransferase
Native Porcine Glutamic-Pyruvic Transaminase
Glutamate-pyruvate transaminase,porcine heart
Glutamic-Pyruvic Transaminase from porcine heart
Alanine Aminotransferase from Human, Recombinant
Alanine Aminotransferase (catalytic concentration)
GLUTAMIC-PYRUVIC TRANSAMINASE, PORCINE H EART, ~100 U/MG
Glutamic-Pyruvic Transaminase from porcine heart lyophilized powder
L-Alanine: 2-Oxoglutarate Aminotransferase, Alanine Aminotransferase (catalytic concentration), GPT
[EINECS(EC#)]

232-561-4
[Molecular Formula]

C11H16N2O6
[MDL Number]

MFCD00131192
[MOL File]

9000-86-6.mol
[Molecular Weight]

272.255
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[form ]

suspension (aqueous)
[color ]

green-yellow
[Water Solubility ]

Dissolves readily at 5 mg/ml in 0.05M potassium phosphate pH 7.5 to give a clear, pale-green solution. Soluble in distilled water or dilute buffer.
[BRN ]

3562140
[EPA Substance Registry System]

Aminotransferase, alanine (9000-86-6)
Safety DataBack Directory
[WGK Germany ]

3
[F ]

10
[TSCA ]

Yes
Hazard InformationBack Directory
[Uses]

It is used for research and clinical diagnostic assays for liver disease. Alanine transaminase (GPT/ALT) is used in multi-analyte clinical chemistry controls and calibrators for major IVD manufacturers. The alanine aminotransferase (ALT) blood test is typically used to detect liver injury. Some of the other applications include Diagnostic Controls, calibrators & standards, immunoassays, clinical chemistry, testing/assay validation, life Science, manufacturing, validation Studies.
[General Description]

Glutamic-pyruvic transaminase (GPT) is localized majorly in the liver.
[Biochem/physiol Actions]

Glutamic-pyruvic transaminase (GPT) mediates the transfer of the amino group to α-ketoglutarate from l-alanine. It plays a key role in gluconeogenesis and amino acid metabolism. The role of GPT in various kinds of tumors has been reported.
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