| Identification | Back Directory | [Name]
GSK-951A) | [CAS]
1403602-33-4 | [Synonyms]
GSK-951A)
GSK 951A
(GSK951A
Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-(1,3-benzodioxol-5-ylmethyl)-5-(4-ethylphenyl)-4,5,6,7-tetrahydro-7-(trifluoromethyl)-, (5R,7S)- | [Molecular Formula]
C24H23F3N4O3 | [MOL File]
1403602-33-4.mol | [Molecular Weight]
472.46 |
| Hazard Information | Back Directory | [Uses]
GSK951A is a THPP analogue. GSK951A inhibits mycolic acid biosynthesis. GSK951A combines potency in culture with in vivo activity and lack of cytotoxicity[1]. | [References]
[1] Cox JA, et al. THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nat Microbiol. 2016;1:15006. DOI:10.1038/nmicrobiol.2015.6 |
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