ChemicalBook--->CAS DataBase List--->1421-86-9

1421-86-9

1421-86-9 Structure

1421-86-9 Structure
IdentificationMore
[Name]

STRYCHNINE HYDROCHLORIDE
[CAS]

1421-86-9
[Synonyms]

STRYCHNINE HCL
STRYCHNINE HYDROCHLORIDE
strychnidin-10-one,monohydrochloride
strychnine,monohydrochloride
Strychnine Hydrochloride Hydrate
[EINECS(EC#)]

215-826-9
[Molecular Formula]

C21H23ClN2O2
[MDL Number]

MFCD00058174
[Molecular Weight]

370.87
[MOL File]

1421-86-9.mol
Chemical PropertiesBack Directory
[Melting point ]

295 °C
[storage temp. ]

Store at RT
[Merck ]

8855
[CAS DataBase Reference]

1421-86-9(CAS DataBase Reference)
[EPA Substance Registry System]

Strychnine hydrochloride (1421-86-9)
Safety DataBack Directory
[Hazard Codes ]

T+,N
[Risk Statements ]

R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed .
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
[Safety Statements ]

S22:Do not breathe dust .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S60:This material and/or its container must be disposed of as hazardous waste .
[RIDADR ]

UN 1692 6.1/PG 1
[WGK Germany ]

3
[RTECS ]

WL2430000
[HazardClass ]

6.1(a)
[PackingGroup ]

I
Hazard InformationBack Directory
[Uses]

Strychnine hydrochloride has been used as a glycine receptor antagonist in the retina for biophysiological functions. It has also been used to block glutamatergic, GABAergic and glycinergic receptors and gap junctions.
[Uses]

Strychnine Hydrochloride acts as an antagonist for cholinesterases and beta amyloid aggregation.
[Definition]

ChEBI: A hydrochloride obtained by combining strychnine with one molar equivalent of hydrogen chloride.
[Biological Activity]

Competitive glycine receptor antagonist; convulsant. Also nicotinic receptor antagonist; displays competitive antagonism at α 7 receptors and non-competitive antagonism at α 4 β 2 receptors.
[Biochem/physiol Actions]

Strychnine is a potent convulsant, which is extracted from Strychnos nux vomica seeds. At high doses, the compound causes convulsions and ultimately death due to respiratory paralysis. Strychnine acts as a respiratory, circulatory and digestive stimulant.
Spectrum DetailBack Directory
[Spectrum Detail]

STRYCHNINE HYDROCHLORIDE(1421-86-9)MS
STRYCHNINE HYDROCHLORIDE(1421-86-9)1HNMR
STRYCHNINE HYDROCHLORIDE(1421-86-9)13CNMR
STRYCHNINE HYDROCHLORIDE(1421-86-9)IR1
STRYCHNINE HYDROCHLORIDE(1421-86-9)IR2
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

1421-86-9(sigmaaldrich)
[TCI AMERICA]

Strychnine Hydrochloride  Hydrate,>98.0%(T)(1421-86-9)
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