| Identification | Back Directory | [Name]
FGIN-1-27 | [CAS]
142720-24-9 | [Synonyms]
FGIN-1-27
FGIN-1-27,98%
N,N-DIHEXYL-2-(4-FLUOROPHENYL)INDOLE-3-ACETAMIDE
N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide
FGIN-1-27N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide | [Molecular Formula]
C28H37FN2O | [MDL Number]
MFCD00467704 | [MOL File]
142720-24-9.mol | [Molecular Weight]
436.6 |
| Chemical Properties | Back Directory | [Appearance]
white to off-white powder | [Melting point ]
96-97 °C | [Boiling point ]
608.3±55.0 °C(Predicted) | [density ]
1.0538 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
methanol: 20 mg/mL
| [form ]
White powder. | [pka]
16.45±0.30(Predicted) | [color ]
Off-white to light yellow | [InChI]
1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3 | [InChIKey]
VUWXAQFLTSBUDB-UHFFFAOYSA-N | [SMILES]
CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c3ccc(F)cc3 |
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white powder | [Biological Activity]
Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC 50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation. | [Uses]
FGIN-1-27 is a potent inositol monophosphatase inhibitor. | [Definition]
ChEBI: 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide is a phenylindole. | [storage]
Room temperature |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|