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1427325-81-2

1427325-81-2 Structure

1427325-81-2 Structure
IdentificationBack Directory
[Name]

(4-ethylnaphthalen-1-yl)-(5-hydroxy-1-pentylindol-3-yl)methanone
[CAS]

1427325-81-2
[Synonyms]

JWH-210 5-hydroxyindole
(4-ethylnaphthalen-1-yl)-(5-hydroxy-1-pentylindol-3-yl)methanone
(4-ethylnaphthalen-1-yl)(5-hydroxy-1-pentyl-1H-indol-3-yl)methanone
Methanone, (4-ethyl-1-naphthalenyl)(5-hydroxy-1-pentyl-1H-indol-3-yl)-
[Molecular Formula]

C26H27NO2
[MOL File]

1427325-81-2.mol
[Molecular Weight]

385.5
Chemical PropertiesBack Directory
[Boiling point ]

601.8±45.0 °C(Predicted)
[density ]

1.13±0.1 g/cm3(Predicted)
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml
[form ]

A crystalline solid
[pka]

9.41±0.40(Predicted)
Hazard InformationBack Directory
[Description]

JWH 210 is a potent cannabimimetic alkylindole that has been identified in extracts from herbal blends. Structurally and functionally similar alkylindoles are rapidly metabolized by the liver and secreted in the urine, with 5-hydroxyindole metabolites detected both in liver secretions and in urine. JWH 210 5-hydroxyindole metabolite is an expected metabolite of JWH 210, detectable both in serum and urine. Its biological activities have yet to be determined.
[References]

[1] J?RG TESKE. Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometry.[J]. Journal of Chromatography B, 2010, 878 27: 2659-2663. DOI: 10.1016/j.jchromb.2010.03.016
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