| Identification | Back Directory | [Name]
ChaMaejasMenin B | [CAS]
89595-71-1 | [Synonyms]
ChaMaejasMenin
Chamaejasmenin A
ChaMaejasMenin B
Chamaejasmenine B
4'-O-Methylsikokianin A
(2S,2'S,3S,3'S)-(+)-Chamaejasmenin B
[3,3'-Bi-4H-1-benzopyran]-4,4'-dione, 2,2',3,3'-tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-methoxyphenyl)-, (2S,2'S,3S,3'S)-
(2S,3S)-3-[(2S,3S)-5,7-dihydroxy-2-(4-methoxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-5,7-dihydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one | [Molecular Formula]
C32H26O10 | [MDL Number]
MFCD10566378 | [MOL File]
89595-71-1.mol | [Molecular Weight]
570.54 |
| Chemical Properties | Back Directory | [Boiling point ]
873.8±65.0 °C(Predicted) | [density ]
1.457±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
7.13±0.60(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Chamaejasmenin B can be extracted from Stellera chamaejasme L. Chamaejasmenin B suppresses cancer cells migration and invasion. Chamaejasmenin B inhibits tumor metastasis. Chamaejasmenin B can be used in the research of cancers, such as breast cancers[1][2]. | [References]
[1] Li Q, et al. Chamaejasmenin B, a novel candidate, inhibits breast tumor metastasis by rebalancing TGF-beta paradox. Oncotarget. 2016 Jul 26;7(30):48180-48192. DOI:10.18632/oncotarget.10193
[2] Li Q, et al. Chamaejasmenin B, an Inhibitor for Metastatic Outgrowth, Reversed M2-Dominant Macrophage Polarization in Breast Tumor Microenvironment. Front Immunol. 2021 Dec 28;12:774230. DOI:10.3389/fimmu.2021.774230 |
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