| Identification | Back Directory | [Name]
Biotin-PEG3-Mal | [CAS]
1431618-70-0 | [Synonyms]
Biotin-PEG3-Mal
Biotin-dPEG??-MAL
Biotin Impurity 29
Biotin-PEG3-amido-Mal
(+)-Biotin-PEG3-NH-Mal
(+)-Biotin-PEG3-NH-Mal
(+)-Biotin-PEG3-Maleimide | [Molecular Formula]
C25H39N5O8S | [MDL Number]
MFCD26142993 | [MOL File]
1431618-70-0.mol | [Molecular Weight]
569.67 |
| Chemical Properties | Back Directory | [Boiling point ]
905.9±65.0 °C(Predicted) | [density ]
1.258±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
Solid | [pka]
13.90±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Biotin-PEG3-Mal is a maleimide Biotinylation reagent that can react with sulfhydryl groups (at pH 6.5-7.5) specifically to form a thioether linkage. | [Uses]
Biotin-PEG3-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329 |
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