| Identification | Back Directory | [Name]
Biotin-PEG7-Amine | [CAS]
1334172-76-7 | [Synonyms]
Biotin-PEG7-NH2
Biotin-PEG7-Amine
Biotin-PEG8-amine
Biotin-dPEG(R)7-NH2
Biotin-PEG7-CH2CH2NH2
alpha-Biotin-omega-amino hepta(ethylene glycol)
N-(23-amino-3,6,9,12,15,18,21-heptaoxatricosyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(23-amino-3,6,9,12,15,18,21-heptaoxatricos-1-yl)hexahydro-2-oxo-, (3aS,4S,6aR)- | [Molecular Formula]
C26H50N4O9S | [MDL Number]
MFCD21363308 | [MOL File]
1334172-76-7.mol | [Molecular Weight]
594.76 |
| Chemical Properties | Back Directory | [Boiling point ]
785.9±60.0 °C(Predicted) | [density ]
1.151±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
solid or viscous liquid | [pka]
13.90±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Biotin-PEG7-amine is a biotin PEG reagent that is reactive with NHS ester or with carboxutlic acid in the presence of EDC or HATU activator. | [Uses]
Biotin-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [reaction suitability]
reaction type: Biotinylations
reagent type: cross-linking reagent | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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Cool Pharm, Ltd
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| Telephone: |
021-60455363 18019463053 |
| Website: |
www.coolpharm.com |
| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Twochem Co.Ltd.
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021-58111628 15800915896 |
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cn.twochem.com |
| Company Name: |
Henan Alfachem Co.,Ltd.
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0371-55051623 18137891487 |
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www.chemicalbook.com/supplier/14555231/ |
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