| Identification | Back Directory | [Name]
Biotin-PEG3-oxyamine | [CAS]
1786206-22-1 | [Synonyms]
Biotin-PEG3-oxyamine
Biotin-PEG3-oxyamine HCl salt
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]ethyl]hexahydro-2-oxo- | [Molecular Formula]
C18H34N4O6S | [MDL Number]
MFCD27952892 | [MOL File]
1786206-22-1.mol | [Molecular Weight]
434.55 |
| Hazard Information | Back Directory | [Description]
Biotin-PEG3-oxyamine is an aldehyde-reactive biotinylation reagent. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. | [Uses]
Biotin-PEG3-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
|