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1441670-89-8

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1441670-89-8 Structure

1441670-89-8 Structure
IdentificationBack Directory
[Name]

ledipasvir interMediate
[CAS]

1441670-89-8
[Synonyms]

Ledipasvir INT 3
Ledipasvir Impurity 9
InterMediate of Ledipasvir
Ledipasvir intermediate N-3
Propanamide,N-(6-hydroxyphenyl)-
5-Azaspiro[2.4]heptane-5-carboxylic acid
ledipasvir interMediate ISO 9001：2015 REACH
TIANFUCHEM--1441670-89-8--ledipasvir interMediate
(6S)-6-[5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol...
(6S)-6- [5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-IH-imidazol-2-yll-5-azaspiro
"(S)-tert-butyl 6-(5-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-1H-iMidazol-2-yl)-5-azaspiro[2.4]"
Tert-butyl (6s)-6-[5-(7-bromo-9,9-difluorofluoren-2-yl)-1h-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylate
(6s)-TERT-BUTYL-6(5(7-BROMO-9,9-DIFLUORO-9h-FLUOREN-2-YI)-1h-IMIDAZOL-2YI)-5-AZASPIRO(2.4)HEPTANE-5-CARBOXYLATE
tert-butyl (S)-6-(5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptane-5-carboxylate
(S)-tert-butyl 6-(5-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-1H-iMidazol-2-yl)-5-azaspiro[2.4]heptane-5-carboxylate
(6S)-tert-butyl-6-(5-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-1H-iMidazol-2-yl)-5-azaspiro[2.4]heptane-5-carboxylate
(S)-tert-butyl 6-(5-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-1H-iMidazol-2-yl)-5-azaspiro[2.4]heptane-5-carboxylate1441670-89-8
(6S)-6-[5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylic acid 1,1-dimethylester
(6S)-6-[5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylic acid 1,1-dimethylethyl ester
(6S)-6-[5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptanes-5-carboxylic acid 1,1-dimethylethyl ester
4)(6S)-6-[5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5- azaspiro[2.4]heptane-5-carboxylic acid 1,1-dimethylethyl ester
5-Azaspiro[2.4]heptane-5-carboxylic acid, 6-[5-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-1H-iMidazol-2-yl]-, 1,1-diMethylethyl ester, (6S)-
(6S)-6-[5-(7- bromo -9,9- difluoro -9H- fluoren -2- yl) -1H- imidazol -2- yl ]-5- azaspiro [2.4] heptane -5- carboxylic acid tert-butyl ester
ledipasvir interMediate ,(6S)-6-[5-(7-BroMo-9,9-difluoro-9H-fluoren-2-yl)-1H-iMidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylic acid 1,1-diMethylethyl ester
[EINECS(EC#)]

939-899-8
[Molecular Formula]

C27H26BrF2N3O2
[MDL Number]

MFCD28386931
[MOL File]

1441670-89-8.mol
[Molecular Weight]

542.41
Chemical PropertiesBack Directory
[Boiling point ]

681.1±55.0 °C(Predicted)
[density ]

1.53±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

11.13±0.10(Predicted)
[Appearance]

Light yellow to brown Solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[REACH Registrations]

Inactive
Raw materials And Preparation ProductsBack Directory
[Raw materials]

1,1-Bis(hydroxymethyl)cyclopropane-->1,1-Bis(iodomethyl)cyclopropane
Hazard InformationBack Directory
[Uses]

Tert-Butyl 6-(5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl) is the key intermediate that could be used to synthesize Ledipasvir which is a direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
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