ChemicalBook--->CAS DataBase List--->144171-61-9

144171-61-9

144171-61-9 Structure

144171-61-9 Structure
IdentificationBack Directory
[Name]

Indoxacarb
[CAS]

144171-61-9
[Synonyms]

2-e][1
(RS)-Form
INDOXACARB
INDOXACARB-MP
rac-Indoxacarb
(+-)-Indoxacarb
Carprofen, Vetranal
INDOXACARB-MP STANDARD
(173584-44-6) indoxacarb
Indoxacarb@100 μg/mL in AcCN
Indoxacarb-MP Reference Material
Indoxacarb@1000 μg/mL in Acetonitrile
indeno[1,2-e][1,3,4}oxadiazine-4a(3h)carboxylic
indeno[1,2-e][1,3,4}oxadiazine-4a(3h)carboxylicacid,7-
cas 144171-61-9 Indoxacarb systemic insecticides for Cotton / vegetables / fruit
indeno[1,2-e][1,3,4}oxadiazine-4a(3h)carboxylicacid,7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(t
indeno[1,2-e][1,3,4}oxadiazine-4a(3h)carboxylicacid,7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoro-methoxy)phenyl]amin
METHYL 7-CHLORO-2,5-DIHYDRO-2-[N-(METHOXYCARBONYL)-4-(TRIFLUOROMETHOXY)ANILINOCARBONYL]INDENO[1,2-E][1,3,4]OXADIAZINE-4A(3H)CARBOXYLATE
(S)-Methyl 7-chloro-2-((Methoxycarbonyl)(4-(trifluoroMethoxy)phenyl)carbaMoyl)-2,3,4a,5-tetrahydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate
Methyl (S)-7-Chloro-2-[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]carbamoyl]-2,3,4a,5-tetrahydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate
7-Chloro-2,5-dihydro-2-(((methoxycarbonyl)(4-(trifluoromethoxy)phenyl)amino)carbonyl)-indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid methyl ester
Indeno(1,2-E)(1,3,4)oxadiazine-4A(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-(((methoxycarbonyl)(4-(trifluoromethoxy)phenyl)amino)carbonyl)-, methyl ester
[Molecular Formula]

C22H17ClF3N3O7
[MDL Number]

MFCD03792834
[MOL File]

144171-61-9.mol
[Molecular Weight]

527.83
Questions And AnswerBack Directory
[Synthesis]

According to relevant literature, the preparation of indoxacarb mainly involves the synthesis of its important intermediates: methyl (+)-5-chloro-2,3-dihydro-2-hydroxy-1-oxo-2H-indene-2-carboxylic acid (compound A) and methyl chlorocarbonyl[4-(trifluoromethoxy)phenyl]carbamate (compound B). The final product, indoxacarb, is then synthesized based on these two intermediates. Based on the order of cyclization and substitution reactions, there are three synthetic routes for indoxacarb: 1 → 2 → 3 (condensation followed by cyclization); 4 → 5 → 6 → 7 (cyclization followed by condensation); and 1 → 8 → 9 → 10 (condensation followed by cyclization). See the diagram below for details.
Indoxacarb Synthesis Route Diagram
Chemical PropertiesBack Directory
[Melting point ]

139-141℃
[Boiling point ]

571.4±60.0 °C(Predicted)
[density ]

1.53
[storage temp. ]

Store at -20°C
[solubility ]

Ethanol: soluble*
[form ]

neat
[pka]

-1.75±0.40(Predicted)
[color ]

White to off-white
[Major Application]

agriculture
environmental
[InChI]

InChI=1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,1-2H3
[InChIKey]

VBCVPMMZEGZULK-NRFANRHFSA-N
[SMILES]

O1C2(C(OC)=O)CC3=C(C2=NN(C(N(C(OC)=O)C2=CC=C(OC(F)(F)F)C=C2)=O)C1)C=CC(Cl)=C3
[EPA Substance Registry System]

Indeno[1,2-e][1, 3,4]oxadiazine-4a(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-[[( methoxycarbonyl)[4-(trifluoromethoxy) phenyl]amino]carbonyl]-, methyl ester(144171-61-9)
Hazard InformationBack Directory
[Uses]

Indoxacarb is an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.
[Uses]

Insecticide.
[Hazard]

A poison by ingestion. Low toxicity by inhalation and skin contact.
[storage]

Store at -20°C
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
GHS06,GHS08,GHS09
[Signal word ]

Danger
[Hazard statements ]

H301-H317-H332-H372-H410
[Precautionary statements ]

P273-P280-P301+P310-P302+P352-P304+P340+P312-P314
[Hazard Codes ]

Xn;N,N,Xn,T
[Risk Statements ]

22-36-43-50/53-57-48/25-20/22
[Safety Statements ]

26-36/37-60-61-45-37-24
[RIDADR ]

UN 3077
[WGK Germany ]

3
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Acute Tox. 3 Oral
Acute Tox. 4 Inhalation
Aquatic Acute 1
Aquatic Chronic 1
Skin Sens. 1B
STOT RE 1
[Toxicity]

LD50 orally in rat: >5000 mg/kg; dermally in rabbit: >2000 mg/kg; LC50 in rat by inhalation: >2 mg/l; LC50 (96 hr) in bluegill sunfish, rainbow trout: >1.0, >0.5 mg/l (Harder)
Spectrum DetailBack Directory
[Spectrum Detail]

Indoxacarb(144171-61-9)1HNMR
144171-61-9 suppliers list
Company Name: Jiangsu Jiannong Plant Protection Co., Ltd.  Gold
Telephone: 0515-68896898
Website: www.jiannong.com
Company Name: Beijing Qinchengyixin Technology Development Co., LTD  Gold
Telephone: 010-67787816; 13811243025
Website: http://www.qinchengyixin.com/
Company Name: Shanghai Boyle Chemical Co., Ltd.  
Telephone: 021-50182298 021-50180596
Website: www.boylechem.com
Company Name: J & K SCIENTIFIC LTD.  
Telephone: 18210857532 18210857532
Website: https://www.jkchemical.com
Company Name: Adamas Reagent, Ltd.  
Telephone: 4006009262 13023226327
Website: www.tansoole.com
Company Name: Chemsky(shanghai)International Co.,Ltd.  
Telephone: 021-50135380
Website: www.shchemsky.com
Company Name: UHN Shanghai Research & Development Co., Ltd.  
Telephone: 021-58958002 18930822973
Website: www.uhnshanghai.com
Company Name: Shanghai Aladdin Bio-Chem Technology Co.,LTD  
Telephone: 400-6206333 13167063860
Website: www.aladdin-e.com/
Company Name: Cantotech Chemicals, Ltd.  
Telephone: 86-0755-86635001
Website: www.cantotech.com
Company Name: Guangzhou Isun Pharmaceutical Co., Ltd  
Telephone: 020-39119399 18927568969
Website: http://www.isunpharm.com
Company Name: Nanjing Sunlida Biological Technology Co., Ltd.  
Telephone: 025-57798810 18652991625
Website:
Company Name: TianJin Alta Scientific Co., Ltd.  
Telephone: 022-65378550-8551
Website: www.altascientific.cn
Company Name: Quality Control Solutions Ltd.  
Telephone: 0755-66853366 13670046396
Website: www.qcsrm.com
Company Name: Shanghai Macklin Biochemical Co.,Ltd.  
Telephone: 15221275939 15221275939
Website: www.macklin.cn
Company Name: Hubei Jusheng Technology Co.,Ltd  
Telephone: 027-59599241 18871490274
Website: http://www.jushengtech.com
Company Name: Chizhou Kailong Import and Export Trade Co., Ltd.  
Telephone:
Website: www.chemicalbook.com/ShowSupplierProductsList16778/0_EN.htm
Company Name: Alta Scientific Co., Ltd.  
Telephone: 022-6537-8550 15522853686
Website: http://www.altascientific.cn
Company Name: Chengdu RunZeBenTu Chemical Co., Ltd  
Telephone: 028-88469284 18000562381;
Website: http://www.rzbtsj.com
Tags:144171-61-9 Related Product Information
104-47-2 143390-89-0 90-05-1 123-11-5 150-76-5 119-36-8 461-82-5 104-94-9 118-55-8 60-32-2 100-66-3 620-81-5 101200-48-0 56-40-6 74223-64-6 456-55-3 101-84-8 79-20-9