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60-32-2

60-32-2 Structure

60-32-2 Structure
IdentificationMore
[Name]

6-Aminocaproic acid
[CAS]

60-32-2
[Synonyms]

6-AMINOCAPROIC ACID
6-AMINOHEXANOIC ACID
6-AMINO-N-CAPROIC ACID
6-AMINO-N-HEXANOIC ACID
6-L-AMINOHEXANOIC ACID
AMINOCAPROIC ACID
EACA
EPSILON-AMINOCAPROIC ACID
EPSILON-AMINO HEXANOIC ACID
EPSILON-AMINO-N-CAPROIC ACID
H-6-AHX-OH
H-ACP(6)-OH
H-ACP-OH
H-AHX(6)-OH
H-E-ACP-OH
H-EPSILON-ACP-OH
H-EPSILON-AHX-OH
H-EPSILON-AMINOCAPROIC ACID
NH2-(CH2)5-COOH
OMEGA-AMINOCAPROIC ACID
[EINECS(EC#)]

200-469-3
[Molecular Formula]

C6H13NO2
[MDL Number]

MFCD00008238
[Molecular Weight]

131.17
[MOL File]

60-32-2.mol
Chemical PropertiesBack Directory
[Appearance]

white crystalline powder
[mp ]

207-209 °C (dec.)(lit.)
[density ]

1.03 g/mL at 20 °C
[Fp ]

207-209°C
[storage temp. ]

2-8°C
[solubility ]

H2O: 50 mg/mL
[form ]

powder
[color ]

white
[Water Solubility ]

SOLUBLE
[Detection Methods]

T,NMR
[Merck ]

14,432
[BRN ]

906872
[CAS DataBase Reference]

60-32-2(CAS DataBase Reference)
[NIST Chemistry Reference]

Hexanoic acid, 6-amino-(60-32-2)
[EPA Substance Registry System]

60-32-2(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

2
[RTECS ]

MO6300000
[HS Code ]

29224995
[Safety Profile]

Moderately toxic by intravenous route. Human systemic effects by ingestion: changes in tubules (includmg acute renal failure, acute tubular necrosis), hematuria, and increased body temperature. Experimental reproductive effects. An eye irritant. When heated to decomposition it emits toxic fumes such as NOx,.
[Hazardous Substances Data]

60-32-2(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
【Raw materials】

Ammonium hydroxide-->Caprolactam-->AMBERLITE IR-120-->Water
【Preparation Products】

Gabexate mesylate-->Capobenic acid-->N-tert-Butoxycarbonyl-1,6-hexanediamine
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

6-Aminohexanoic acid(60-32-2).msds
Questions And AnswerBack Directory
[Description]

6-aminocaproic acid (Brand name: Amicar) is a kind of synthetic derivative of lysine. Since it is a analogue of amino acid lysine, it can act as the inhibitor for enzymes that need to bind to that particular lysine residue, e.g. the proteolytic enzyme such as plasmin, which is responsible for fibrinolysis. Therefore, it has anti-fibrinolytic activity. It also competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin. Based on this property, it can be used for the treatment of acute bleeding due to elevated fibrinolytic activity in many clinical situations. It can also indicated by FDA for the prevention of recurrent hemorrhage in patients of traumatic hyphema. It may also act as a prophylactic against the vascular disease due to its inhibitory effect on the formation of lipoprotein which is the risk factor of vascular disease.
[References]

https://pubchem.ncbi.nlm.nih.gov/compound/6-aminohexanoic_acid#section=Pharmacology-and-Biochemistry
https://en.wikipedia.org/wiki/Aminocaproic_acid
Spectrum DetailBack Directory
[Spectrum Detail]

6-Aminocaproic acid(60-32-2) 1H NMR
6-Aminocaproic acid(60-32-2) IR1
6-Aminocaproic acid(60-32-2) Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

6-Aminocaproic acid, 99+%(60-32-2)
[Alfa Aesar]

6-Aminohexanoic acid, 99+%(60-32-2)
[Sigma Aldrich]

60-32-2(sigmaaldrich)
[TCI AMERICA]

6-Aminohexanoic Acid,>98.0%(T)(60-32-2)
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