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1445846-30-9

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1445846-30-9 Structure

1445846-30-9 Structure
IdentificationBack Directory
[Name]

GPR84 antagonist 8
[CAS]

1445846-30-9
[Synonyms]

GPR84 antagonist 8
GPR84 antagonist 8,GPR-84 antagonist 8
4H-Pyrimido[6,1-a]isoquinolin-4-one, 2-(1,4-dioxan-2-ylmethoxy)-6,7-dihydro-9-(2-pyridinylmethoxy)-
[Molecular Formula]

C23H23N3O5
[MDL Number]

MFCD31692401
[MOL File]

1445846-30-9.mol
[Molecular Weight]

421.45
Chemical PropertiesBack Directory
[Boiling point ]

628.2±65.0 °C(Predicted)
[density ]

1.38±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 5 mg/mL (11.86 mM)
[form ]

Solid
[pka]

3.98±0.12(Predicted)
[color ]

Off-white to light yellow
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

GPR84 antagonist 8 is a selective GPR84 antagonist.
[References]

[1] Recio C, et al. Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages. Front Immunol. 2018 Jun 20;9:1419. DOI:10.3389/fimmu.2018.01419
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