| Identification | Back Directory | [Name]
Amino-PEG1-acid | [CAS]
144942-89-2 | [Synonyms]
NH2-PEG1-COOH
Amino-PEG1-acid
Amino-PEG1-COOH
Amino-PEG1-C2-acid
Amino-PEG1-propionic acid
3-(2-Aminoethoxy)propanoic acid
Propanoic acid, 3-(2-aminoethoxy)- | [Molecular Formula]
C5H11NO3 | [MDL Number]
MFCD22017475 | [MOL File]
144942-89-2.mol | [Molecular Weight]
133.15 |
| Chemical Properties | Back Directory | [Boiling point ]
284.7±20.0 °C(Predicted) | [density ]
1.150±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Soluble in Water, DMSO, DMF | [form ]
Solid | [pka]
4.17±0.10(Predicted) | [color ]
White | [InChI]
InChI=1S/C5H11NO3/c6-2-4-9-3-1-5(7)8/h1-4,6H2,(H,7,8) | [InChIKey]
ZCQVVSMJNBNDAQ-UHFFFAOYSA-N | [SMILES]
C(O)(=O)CCOCCN |
| Hazard Information | Back Directory | [Description]
Amino-PEG1-acid is a PEG linker containing an amino group (NH2) with a terminal carboxylic acid (CO2H). NH2 group is reactive with carboxylic acids in the presence of coupling reagent such as EDC , or directly with NHS esters, to form a stable amide bond. | [Uses]
Amino-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956 |
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https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
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