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1453117-42-4

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1453117-42-4 Structure

1453117-42-4 Structure
IdentificationBack Directory
[Name]

Tos-PEG4-acid
[CAS]

1453117-42-4
[Synonyms]

Tos-PEG4-acid
Propanoic acid, 3-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]-
[Molecular Formula]

C16H24O8S
[MDL Number]

MFCD29052202
[MOL File]

1453117-42-4.mol
[Molecular Weight]

376.42
Chemical PropertiesBack Directory
[Boiling point ]

548.3±50.0 °C(Predicted)
[density ]

1.256±0.06 g/cm3(Predicted)
[pka]

4.27±0.10(Predicted)
Hazard InformationBack Directory
[Description]

Tos-PEG4-acid is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
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