| Identification | More | [Name]
2-HYDROXY-5-METHYLBENZOPHENONE | [CAS]
1470-57-1 | [Synonyms]
2'-HYDROXY 5'-METHYL BENZOPHENONE
2-HYDROXY-5-METHYLBENZOPHENONE
RARECHEM FH 1L 0064
(2-Hydroxy-5-methylphenyl)phenylmethanone
2-Benzoyl-4-methylphenol
5-Methyl-2-hydroxybenzophenone
Benzophenone, 2-hydroxy-5-methyl-
Methanone, (2-hydroxy-5-methylphenyl)phenyl- | [EINECS(EC#)]
216-002-1 | [Molecular Formula]
C14H12O2 | [MDL Number]
MFCD00002379 | [Molecular Weight]
212.24 | [MOL File]
1470-57-1.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow crystalline powder | [Melting point ]
83-85 °C (lit.) | [Boiling point ]
312.08°C (rough estimate) | [density ]
1.1035 (rough estimate) | [refractive index ]
1.6000 (estimate) | [form ]
powder to crystal | [pka]
8.24±0.43(Predicted) | [color ]
Light orange to Yellow to Green | [CAS DataBase Reference]
1470-57-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29145000 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow crystalline powder | [Uses]
2-?Hydroxy-?5-?methylbenzophenone is a general reagent used in the synthesis of anti-bacterial and anti-fungal agents. | [Preparation]
Preparation by condensation of benzotrichloride with p-cresol,
? in the presence of aluminium chloride in carbon disulfide for 2 h (75%). The 6,12-diphenyl-2,8-dimethyl-6,12-epoxy-6H,12H-dibenzo[b,f] dioxocin, an intermediate compound, was also formed under these conditions (29%). This “dioxocin”, by hydrolysis with concentrated sulfuric acid at r.t., gave the expected ketone (91%);
? in the presence of aqueous sodium hydroxide in a water bath for 4 h (33%) or in 32–40% aqueous sodium hydroxide at 70–80° (67%). | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 38, p. 1924, 1973 DOI: 10.1021/jo00950a030 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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