| Identification | Back Directory | [Name]
1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol | [CAS]
1472-62-4 | [Synonyms]
(+/-)-N-methylcoclaurine
1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl- | [Molecular Formula]
C18H21NO3 | [MOL File]
1472-62-4.mol | [Molecular Weight]
299.36 |
| Chemical Properties | Back Directory | [Melting point ]
138 °C | [Boiling point ]
480.9±45.0 °C(Predicted) | [density ]
1.214±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
10.00±0.15(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
(±)-N-Methylcoclaurine is a selective α2-adrenoceptor antagonist[1]. | [References]
[1] H H Pauli, et al. Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis. Plant J. 1998 Mar;13(6):793-801. DOI:10.1046/j.1365-313x.1998.00085.x |
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