| Identification | Back Directory | [Name]
Coclaurine | [CAS]
2196-60-3 | [Synonyms]
Coclaurine
Sanjoinine K
(+)-Coclaurine
(R)-Coclaurine
(R)-1,2,3,4-Tetrahydro-1-(4-hydroxybenzyl)-6-methoxyisoquinolin-7-ol
(1R)-1-(4-Hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-7-ol
(1R)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-7-isoquinolinol
7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-, (1R)- | [Molecular Formula]
C17H19NO3 | [MDL Number]
MFCD19707510 | [MOL File]
2196-60-3.mol | [Molecular Weight]
285.34 |
| Hazard Information | Back Directory | [Chemical Properties]
Coclaurine is a white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents. | [Uses]
Coclaurine is a tetrahydroisoquinoline alkaloid with anti-aging activity,used as a nicotinic acetylcholine receptor antagonis. | [Definition]
ChEBI:(R)-coclaurine is a coclaurine. It is an enantiomer of a (S)-coclaurine. | [in vivo]
An intracerebroventricular injection of (+)-Coclaurine (d-Coclaurine; 50 μg) produces a slight increase in 3,4-dihydroxyphenylacetic acid level and a significant increase in homovanillic acid level in the mouse striatum. (+)-Coclaurine blocks postsynaptic but not presynaptic dopamine receptors in the mouse striatum[2]. |
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