| Identification | More | [Name]
2,6-DICHLOROPYRIDINE-3-BORONIC ACID | [CAS]
148493-34-9 | [Synonyms]
2,6-DICHLORO-3-PYRIDINEBORONIC ACID
(2,6-DICHLORO-3-PYRIDINYL)-BORONIC ACID
2,6-DICHLORO-3-PYRIDYL BORONIC ACID
2,6-DICHLOROPYRIDIN-3-YLBORONIC ACID
2,6-DICHLOROPYRIDINE-3-BORONIC ACID
2,6-Dichloropyridine-3-Boronic | [Molecular Formula]
C5H4BCl2NO2 | [MDL Number]
MFCD03094989 | [Molecular Weight]
191.81 | [MOL File]
148493-34-9.mol |
| Questions And Answer | Back Directory | [Synthesis]
At -78°C, a 1.55 M n-butyllithium/n-hexane solution (20 mL) was added dropwise to a solution of diisopropylamine (4 mL) in THF (60 mL), and the mixture was stirred at the same temperature for 30 minutes. A mixture of 2,6-dichloropyridine (2.0 g) and THF (10 mL) was added dropwise to this solution, and the mixture was stirred at the same temperature for another 1 hour. A mixture of triisopropyl borate (6.8 mL) and THF (10 mL) was added dropwise, and the mixture was stirred at room temperature for 20 hours. The reaction mixture was diluted with water, neutralized with hydrochloric acid, and extracted with ethyl acetate. The organic layer was washed with water, dried over magnesium sulfate, and concentrated under reduced pressure. 2,6-DICHLOROPYRIDINE-3-BORONIC ACID (2.6 g) was obtained. 
| [Application]
Literature reports that 2,6-dichloro-3-pyridineboronic acid can be used to prepare novel dihaloacetylated heterocyclic pyrethroids. |
| Chemical Properties | Back Directory | [Melting point ]
150°C(lit.) | [Boiling point ]
373.7±52.0 °C(Predicted) | [density ]
1.56±0.1 g/cm3(Predicted) | [storage temp. ]
Keep Cold | [form ]
powder | [pka]
6.40±0.58(Predicted) | [color ]
White | [InChI]
InChI=1S/C5H4BCl2NO2/c7-4-2-1-3(6(10)11)5(8)9-4/h1-2,10-11H | [InChIKey]
XBBLBQZAVMHEER-UHFFFAOYSA-N | [SMILES]
B(C1=CC=C(Cl)N=C1Cl)(O)O | [CAS DataBase Reference]
148493-34-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
22-36/37/38 | [Safety Statements ]
26-37 | [WGK Germany ]
WGK 3 | [Hazard Note ]
Harmful/Irritant/Keep Cold | [HazardClass ]
IRRITANT | [HS Code ]
29333990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|