| Identification | More | [Name]
Naftalofos | [CAS]
1491-41-4 | [Synonyms]
NAFTALOFOS
NAPHTHALOPHOS
2-((diethoxyphosphinyl)oxy)-1h-benz(de)isoquinoline-3(2h)-dione
b-9002
bayer25820
bayer9002
bayers940
chemagrob-9002
e9002
ent25,567
maretin
n-hydroxy-naphthalimiddiethylphosphate
n-hydroxynaphthylimidediethylphosphate
o,o-diethyln-hydroxynaphthalimidephosphate
phosphoricacid,diethylester,naphthalimidoderiv.
phosphoricacid,diethylester,n-naphthalimidederiv.
phtalophos
rametin
rawetin
diethyl naphthalene-1,8-dicarboximidooxyphosphonate | [EINECS(EC#)]
216-078-6 | [Molecular Formula]
C16H16NO6P | [MDL Number]
MFCD00864515 | [Molecular Weight]
349.28 | [MOL File]
1491-41-4.mol |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R24/25:Toxic in contact with skin and if swallowed . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
2783 | [WGK Germany ]
3 | [RTECS ]
QK5775000 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
chicken,LD50,oral,43300ug/kg (43.3mg/kg),PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Toxicology and Applied Pharmacology. Vol. 11, Pg. 49, 1967. |
| Hazard Information | Back Directory | [Uses]
Anthelmintic(veterinary). | [Definition]
ChEBI: Naftalofos is an organic heterotricyclic compound. It has a role as an anthelminthic drug. | [Brand name]
Maretin (Bayer Animal Health). | [Mechanism of action]
Acetylcholinesterase (AChE) inhibitor. | [Synthesis]
Naftalofos is synthesised through a multi-step chemical process that
begins with the preparation of O-ethyl phenylphosphonothioic acid, which
serves as the phosphorus-containing core. This intermediate is then
reacted with 2-naphthol, a hydroxylated aromatic compound, via
esterification, forming the characteristic O-naphthyl linkage. After the
coupling step, the crude product undergoes purification to isolate. | [Pesticide Type]
Insecticide; Veterinary substance |
|
| Company Name: |
AFINE CHEMICALS LIMITED
|
| Telephone: |
+86-571-85134551 +86-18958018566 |
| Website: |
www.afinechem.com/index.html |
|