| Identification | Back Directory | [Name]
RO 23-9358 | [CAS]
153125-17-8 | [Synonyms]
Ro 23-9358 >=97% (HPLC), solid
N-(carboxymethyl)-N-(3,5-bis(decyloxy)-phenyl)glycine
Glycine, N-[3,5-bis(decyloxy)phenyl]-N-(carboxyMethyl)- | [Molecular Formula]
C30H51NO6 | [MDL Number]
MFCD00923024 | [MOL File]
153125-17-8.mol | [Molecular Weight]
521.73 |
| Chemical Properties | Back Directory | [Melting point ]
99.5-110 °C | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble16mg/mL | [form ]
solid | [color ]
white | [InChIKey]
SWOCSPJYINCHOW-UHFFFAOYSA-N | [SMILES]
CCCCCCCCCCOc1cc(OCCCCCCCCCC)cc(c1)N(CC(O)=O)CC(O)=O |
| Hazard Information | Back Directory | [Uses]
Ro 23-9358 is a potent secretory phospholipase A2 inhibitor with anti-inflammatory activity[1]. | [Biological Activity]
Diacylglycerol lipase inhibitor. Target for anti-obesity drugs. | [IC 50]
PLA2 | [References]
[1] R A LeMahieu, et al. N-(carboxymethyl)-N-[3,5-bis(decyloxy)-phenyl]glycine (Ro 23-9358): a potent inhibitor of secretory phospholipases A2 with antiinflammatory activity. J Med Chem. 1993 Oct 1;36(20):3029-31. DOI:10.1021/jm00072a025 |
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| Company Name: |
Energy Chemical
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| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
TargetMol
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| Telephone: |
400-821-0310 15002144251 |
| Website: |
www.targetmol.cn/ |
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