ChemicalBook--->CAS DataBase List--->154229-20-6

154229-20-6

154229-20-6 Structure

154229-20-6 Structure
IdentificationBack Directory
[Name]

Anhydro Abiraterone
[CAS]

154229-20-6
[Synonyms]

Anhydro Abiraterone
Abiraterone Acetate IMP
Abiraterone Anhydro Impurity
Abiraterone ImpurityABCDEFGHI
3-((8R,9S,10R,13S,14S)-10,13-dimethyl
17-(Pyridin-3-yl)androsta-3,5,16-triene
Pyridine, 3-androsta-3,5,16-trien-17-yl-
Abiraterone acetate impurity 1 (abiraterone)
Anhydro Abiraterone/17-(Pyridin-3-yl)androsta-3,5,16-triene
3-((8R,9S,10R,13S,14S)-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15- decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine
[Molecular Formula]

C24H29N
[MDL Number]

MFCD00924101
[MOL File]

154229-20-6.mol
[Molecular Weight]

331.49
Chemical PropertiesBack Directory
[Melting point ]

118 - 122°C
[Boiling point ]

475.0±45.0 °C(Predicted)
[density ]

1.10±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

5.31±0.12(Predicted)
[color ]

Off-White to Pale Beige
[Major Application]

pharmaceutical small molecule
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Aquatic Chronic 1
Repr. 2
STOT RE 2
Hazard InformationBack Directory
[Uses]

Anhydro Abiraterone is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
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