ChemicalBook--->CAS DataBase List--->853-23-6

853-23-6

853-23-6 Structure

853-23-6 Structure
IdentificationBack Directory
[Name]

Dehydroepiandrosterone acetate
[CAS]

853-23-6
[Synonyms]

skf2847
PRASTERONE ACETATE
androstenoloneacetate
dehydroandrosterone 3-acetate
3β-Acetoxyandrost-5-en-17-one
3B-ACETOXY-5-ANDROSTEN-17-ONE
DEHYDROISOANDROSTERONE ACATATE
DEHYDROISOANDROSTERONE ACETATE
Dehydroepiandrosterone acetate
3-β-acetoxy-5-androsten-17-one
3β-Acetoxy-5-androstene-17-one
3β-Acetyloxyandrost-5-en-17-one
DEHYDROEPIANDROSTERONE-3-ACETATE
DEHYDROISOANDROSTERONE 3-ACETATE
3BETA-ACETOXY-5-ANDROSTEN-17-ONE
5-ANDROSTEN-3-BETA-ACETOXY-3-ONE
17-Oxoandrost-5-en-3β-yl Acetate
DHEA Acetate (Prasterone acetate)
3-(ACETYLOXY)ANDROST-5-ENE-17-ONE
TRANS-DEHYDROANDROSTERONE ACETATE
17-Oxoandrost-5-ene-3β-yl=acetate
3-beta-acetoxydehydroepiandrosterone
5-ANDROSTEN-3-BETA-OL-17-ONE ACETATE
3B-HYDROXYANDROST-5-EN-17-ONEACETATE
5-ANDROSTEN-3BETA-OL-17-ONE 3-ACETATE
(3β)-3-(Acetyloxy)androst-5-en-17-one
3b-Hydroxy-5-androstene-17-one acetate
3β-Hydroxy-5-androstene-17-one Acetate
3-beta-hydroxy-andrest-5-en-17-onacetate
3-beta-hydroxy-androst-5-en-17-onacetate
3-beta-hydroxyandrost-5-en-17-oneacetate
3BETA-ACETOXY-5-ANDROSTEN-17-ONE ACETATE
Androst-5-en-17-one,3-(acetyloxy)-, (3b)-
DEHYDROISOANDROSTERONE 3-ACETATECRYSTALL INE
3-β-Acetoxy-5-androsten-17-one, Prasterone acetate
Dehydroepiandrosterone acetate Prasterone acetate
trans-Dehydroandrosterone Acetate Dehydroisoandrosterone Acetate
ACETIC ACID DIMETHYL-OXO-TETRADECAHYDRO-1H-CYCLOPENTA(A)PHENANTHREN-3-YL ESTER
Dehydroisoandrosterone 3-acetate,3-β-Acetoxy-5-androsten-17-one, Prasterone acetate
DHA, (10,13-DIMETHYL-17-OXO-1,2,3,4,7,8,9,11,12,14,15,16-DODECAHYDROCYCLOPENTA[A]PHENANTHREN-3-YL) ACETATE
[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate
[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] ethanoate
(3S,8R,9S,10R,13S)-10,13-dimethyl-17-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate
acetic acid [(3S,8R,9S,10R,13S,14S)-17-keto-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] ester
(3S,8R,9S,10R,13S,14S)-10,13-diMethyl-17-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate
ACETIC ACID (3S,8R,9S,10R,13S,14S)-10,13-DIMETHYL-17-OXO-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ESTER
[EINECS(EC#)]

212-714-1
[Molecular Formula]

C21H30O3
[MDL Number]

MFCD00021119
[MOL File]

853-23-6.mol
[Molecular Weight]

330.46
Chemical PropertiesBack Directory
[Melting point ]

168-170 °C(lit.)
[Boiling point ]

407.89°C (rough estimate)
[density ]

1.0998 (rough estimate)
[vapor pressure ]

0Pa at 20℃
[refractive index ]

1.5192 (estimate)
[storage temp. ]

Refrigerator
[solubility ]

Chloroform, DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Optical Rotation]

[α]20/D +2.4°, c = 2 in ethanol
[Water Solubility ]

11.5mg/L(temperature not stated)
[InChI]

InChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3
[InChIKey]

NCMZQTLCXHGLOK-KJBVPOJVSA-N
[SMILES]

C[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,13,15,21,25,r|
[LogP]

5.1 at 20℃
[CAS DataBase Reference]

853-23-6
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Danger
[Hazard statements ]

H360
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[RTECS ]

BV8396810
[REACH Registrations]

Active
Raw materials And Preparation ProductsBack Directory
[Preparation Products]

Epiandrosterone acetate-->Methandriol-->3β-Acetyloxy-14α-hydroxy-5α-androstan-17-one-->Androst-5-en-17-one,3-chloro-, (3b)--->Androstenone hydrazone
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

A metabolite of Dehydroepiandrosterone. This mammalian pro-hormone promotes brain and immune function
[Uses]

Menopausal syndrome
[Application]

Dehydroepiandrosterone acetate (CAS No: 853-23-6, abbreviated as DHEA acetate) is an important pharmaceutical intermediate. It can be used as a raw material to produce testosterone, methyl testosterone, estradiol, and estriol. Recently, with the development of the pharmaceutical industry, more and more applications for DHEA acetate have been exploited[1].
[Definition]

ChEBI:Prasterone acetate is a steroid ester.
[Flammability and Explosibility]

Notclassified
[Biological Activity]

Dehydroepiandrosterone acetate (DHEA, Androstenolone) is a kind of dehydroepiandrosterone derivatives. DHEA is an endogenous steroid hormone, which is considered to be a natural product/dietary supplement with many proposed benefits to humans.
[in vivo]

Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.
[storage]

Store at -20°C
[References]

[1] Chao Cheng. “Solubility determination and thermodynamic models for dehydroepiandrosterone acetate in mixed solvents of (ethyl acetate + methanol), (ethyl acetate + ethanol) and (ethyl acetate + isopropanol).” Journal of Chemical Thermodynamics 101 (2016): Pages 372-379.
Spectrum DetailBack Directory
[Spectrum Detail]

Dehydroepiandrosterone acetate(853-23-6)MS
Dehydroepiandrosterone acetate(853-23-6)1HNMR
Dehydroepiandrosterone acetate(853-23-6)13CNMR
Dehydroepiandrosterone acetate(853-23-6)IR1
Dehydroepiandrosterone acetate(853-23-6)Raman
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