| Identification | Back Directory | [Name]
3-Pyridinecarboxylic acid, 1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-1,2,5,6-tetrahydro- | [CAS]
159094-94-7 | [Synonyms]
3-Pyridinecarboxylic acid, 1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-1,2,5,6-tetrahydro- | [Molecular Formula]
C21H22N2O3 | [MOL File]
159094-94-7.mol | [Molecular Weight]
350.41 |
| Hazard Information | Back Directory | [Uses]
NO-711 (NNC-711) free acid is a novel potent and selective inhibitor of γ-aminobutyric acid uptake. NO-711 inhibits synaptosomal (IC50 = 47 nM), neuronal (IC50 = 1238 nM) and glial (IC50 = 636 nM) GABA uptake in vitro[1]. | [Definition]
ChEBI: 1-[2-[(diphenylmethylene)amino]oxyethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid is a diarylmethane. | [References]
[1] P D Suzdak, et al. NNC-711, a novel potent and selective gamma-aminobutyric acid uptake inhibitor: pharmacological characterization. Eur J Pharmacol. 1992 Dec 2;224(2-3). DOI:10.1016/0014-2999(92)90804-d |
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