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1603814-04-5

1603814-04-5 Structure

1603814-04-5 Structure
IdentificationBack Directory
[Name]

3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib
[CAS]

1603814-04-5
[Synonyms]

Desfluoro Gefitinib
Gefitinib Impurity 16
Gefitinib Impurity HCl
Gefitinib EP impurity B
Gefitinib related substance B
3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib
N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Gefitinib Impurity HCl (3-Deschloro-4-Desfluoro-4-Chloro-3-Fluoro Gefitinib HCl)
N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine
4-Quinazolinamine, N-(4-chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-
[Molecular Formula]

C22H24ClFN4O3
[MDL Number]

MFCD29039079
[MOL File]

1603814-04-5.mol
[Molecular Weight]

446.9
Chemical PropertiesBack Directory
[Melting point ]

180-183oC
[Boiling point ]

585.0±50.0 °C(Predicted)
[density ]

1.322±0.06 g/cm3(Predicted)
[storage temp. ]

Refrigerator
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
[form ]

Solid
[pka]

7.00±0.10(Predicted)
[color ]

Off-White to Light Brown
Hazard InformationBack Directory
[Uses]

3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib is an impurity of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).
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