ChemicalBook--->CAS DataBase List--->160738-57-8

160738-57-8

160738-57-8 Structure

160738-57-8 Structure
IdentificationMore
[Name]

Gatifloxacin hydrochloride
[CAS]

160738-57-8
[Synonyms]

1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid hydrochloride
gatifloxacin hydrochloride
GATIFLOXACIN LACTATE
Gatifloxacin acid ester
Gatifloxacin base
4-dihydroquinoline-3-carboxylic acid
GatifloxacineHCL
1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylicac
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid hydrochloride
[EINECS(EC#)]

1308068-626-2
[Molecular Formula]

C22H28FN3O7
[MDL Number]

MFCD08063913
[Molecular Weight]

465.47
[MOL File]

160738-57-8.mol
Chemical PropertiesBack Directory
[Melting point ]

162 C
[InChIKey]

CFPJUGZAXVMNBA-UHFFFAOYSA-N
[SMILES]

N1(C=C(C(O)=O)C(=O)C2C=C(F)C(N3CCNC(C)C3)=C(OC)C1=2)C1CC1.C(O)(C(C)O)=O
[CAS DataBase Reference]

160738-57-8(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
[HS Code ]

29419000
Raw materials And Preparation ProductsBack Directory
[Raw materials]

2,4,5-Trifluoro-3-methoxybenzoic acid
Hazard InformationBack Directory
[Description]

Gatifloxacin is a novel orally-active fluoroquinolone antibiotic with a potent and broad spectrum of activity against gram-positive (S.pneumonia, S.aureus) and gram-negative bacteria. It shows good activity against strains resistant to established antituberculosis agents. Gatifloxacin was marketed for the treatment of respiratory tract and urinary infections, particularly the treatment of certain community-acquired infections (such as bronchitis, pneumonia and common sexually-transmitted diseases). Comparative studies with ciprofloxacin, ofloxacin and sparfloxacin against fluoroquinolone-resistant organisms indicated a better or equivalent effectiveness with less phototoxic adverse effects.
[Chemical Properties]

pale yellow prisms
[Originator]

Kyori (Japan)
[Uses]

Gatifloxacin hydrochloride is a fourth-generation quinolone broad-spectrum antibacterial drug that is effective against common Gram-positive, Gram-negative, and atypical pathogens. It is a newer and replacement product for ofloxacin, ciprofloxacin, and levofloxacin.
[Brand name]

Tequin
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