| Identification | Back Directory | [Name]
Propargyl-PEG4-Maleimide | [CAS]
1609651-90-2 | [Synonyms]
Alkyne-PEG4-NH-Mal
PROPARGYL-PEG4-AMIDO-MAL
Propargyl-PEG4-Maleimide
Propargyl-PEG4-amido-Maleimide
Alkyne-PEG4-Maleimide,Propargyl-PEG4-Maleimide
1H-Pyrrole-1-propanamide, 2,5-dihydro-2,5-dioxo-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl-
3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)propanamide | [Molecular Formula]
C18H26N2O7 | [MDL Number]
MFCD22380740 | [MOL File]
1609651-90-2.mol | [Molecular Weight]
382.41 |
| Hazard Information | Back Directory | [Uses]
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
csynbio
|
| Telephone: |
15051477682 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList1949820/0_EN.htm |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
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