| Identification | Back Directory | [Name]
Propargyl-PEG6-Br | [CAS]
1973383-30-0 | [Synonyms]
Propargyl-PEG6-Br
Propargyl-PEG6-bromide
1-bromo-3,6,9,12,15,18-hexaoxahenicos-20-yne | [Molecular Formula]
C15H27BrO6 | [MDL Number]
MFCD32263749 | [MOL File]
1973383-30-0.mol | [Molecular Weight]
383.28 |
| Hazard Information | Back Directory | [Biological Activity]
Propargyl-PEG6-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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| Company Name: |
Bide Pharmatech Ltd.
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| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
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