| | Identification | More |  | [Name] 
 Adenosine-5'-diphosphate disodium salt
 |  | [CAS] 
 16178-48-6
 |  | [Synonyms] 
 5'-ADENYLDIPHOSPHORIC ACID, DISODIUM SALT
 5'-ADP-NA2
 ADENOSINE-5'-DIPHOSPHATE DISODIUM
 ADENOSINE-5'-DIPHOSPHATE DISODIUM SALT
 ADENOSINE-5'-DIPHOSPHATE NA2-SALT
 ADENOSINE-5'-DIPHOSPHORIC ACID, DISODIUM
 ADENOSINE-5'-DIPHOSPHORIC ACID SODIUM SALT
 ADENOSINE 5'-PYROPHOSPHATE, DISODIUM SALT
 ADENOSINE DIPHOSPHATE DINA SALT
 ADP
 ADP 2NA
 ADP DISODIUM
 ADP DISODIUM SALT
 ADP NA2
 ADP, NA2H
 adenosine5’-(trihydrogendiphosphate),disodiumsalt
 5'-ADP-Na2
 Adenosine5Diphosphate,Disodium,Dihydrate
 ADENOSINE-5-DIPHOSPHORIC ACID TRI SODIUIM SALT (A.D.P.)
 ADENOSINE-5'-DIPHOSPHORIC ACID DISODIUM SALT
 |  | [EINECS(EC#)] 
 240-314-7
 |  | [Molecular Formula] 
 C10H13N5Na2O10P2
 |  | [MDL Number] 
 MFCD00066635
 |  | [Molecular Weight] 
 471.16
 |  | [MOL File] 
 16178-48-6.mol
 | 
 | Chemical Properties | Back Directory |  | [Appearance] 
 White crystalline powder
 |  | [storage temp. ] 
 −20°C
 
 |  | [form ] 
 Powder
 |  | [color ] 
 White
 |  | [Optical Rotation] 
 [α]20/D 29.6±1°, c = 0.5% in 0.5 M Na2HPO4
 |  | [Water Solubility ] 
 Soluble in water.
 |  | [Sensitive ] 
 Hygroscopic
 |  | [BRN ] 
 3645656
 |  | [InChIKey] 
 AIZARHCNBKWDRW-KWIZKVQNSA-L
 |  | [SMILES] 
 [Na+].[Na+].C(OP(=O)(O)OP(O)(O)=O)[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H]([O-])[C@@H]1[O-]
 |  | [CAS DataBase Reference] 
 16178-48-6(CAS DataBase Reference)
 |  | [EPA Substance Registry System] 
 16178-48-6(EPA Substance)
 | 
 | Safety Data | Back Directory |  | [Hazard Codes ] 
 Xi
 |  | [Risk Statements ] 
 R36/37/38:Irritating to eyes, respiratory system and skin .
 |  | [Safety Statements ] 
 S22:Do not breathe dust .
 S24/25:Avoid contact with skin and eyes .
 S36:Wear suitable protective clothing .
 S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
 |  | [WGK Germany ] 
 3
 
 |  | [F ] 
 10-21
 |  | [TSCA ] 
 Yes
 |  | [HS Code ] 
 29349990
 | 
 | Hazard Information | Back Directory |  | [Description] 
 Adenosine-5'-diphosphate disodium salt is a sodium salt of adenosine 5'-diphosphate. Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.
 |  | [Chemical Properties] 
 White crystalline powder
 |  | [Uses] 
 Adenosine-5'-diphosphate disodium salt is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
 |  | [Application] 
 Adenosine-5'-diphosphate disodium salt is found in the extract of plants such as salvianolic acid and rhizoma gastrodiae, as well as in dinucleotide phosphate. This product has been shown to have cardioprotective effects against ischemia reperfusion injury in animal models. It also has congestive heart failure activity, which may be due to its ability to relax vascular smooth muscle and increase the diameter of lymphatic vessels.
 |  | [Reactions] 
 Adenosine-5'-diphosphate disodium salt can participate in a variety of enzymatic reactions in organisms.
 |  | [Biochem/physiol Actions] 
 Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with purinergic receptors P2Y1 and  P2Y12.  Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.
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