| Identification | Back Directory | [Name]
Broussoflavonol F | [CAS]
162558-94-3 | [Synonyms]
Broussoflavonol F
3,5,7-Trihydroxy-2-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-8-(3-methyl-2-buten-1-yl)- | [Molecular Formula]
C25H26O6 | [MDL Number]
MFCD29765862 | [MOL File]
162558-94-3.mol | [Molecular Weight]
422.47 |
| Chemical Properties | Back Directory | [Boiling point ]
640.9±55.0 °C(Predicted) | [density ]
1.315±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
6.43±0.40(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Description]
Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggregation.
Broussoflavonol F shows inhibitory activities on mushroom tyrosinase.
3. Broussoflavonol F shows radical scavenging against 2,2-diphenyl-1-picrylhydrazyl (DPPH), the IC50 value of 708.54 uM.
4. Broussoflavonol F exhibits moderate cytotoxic activities against five human cancer cells with the IC50 value of 0.41-7.2 ug/mL. | [Uses]
Broussoflavonol F possess xanthine oxidase inhibitory activity[1]. | [target]
Tyrosinase | [References]
[1] Ryo Miyata, et al. Propolis Components from Stingless Bees Collected on South Sulawesi, Indonesia, and Their Xanthine Oxidase Inhibitory Activity. J Nat Prod. 2019 Feb 22;82(2):205-210. DOI:10.1021/acs.jnatprod.8b00541 |
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