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165800-03-3

165800-03-3 Structure

165800-03-3 Structure
IdentificationMore
[Name]

Linezolid
[CAS]

165800-03-3
[Synonyms]

ACETAMIDE, N-[[(5S)-3-[3-FLUORO-4-(4-MORPHOLINYL)PHENYL]-2-OXO-5-OXAZOLIDINYL]METHYL]-
LINEZOLID
LINEZOLIDE
(s)-n-[[3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide
Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-(9CI)
Acetamide, N-[[3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, (S)-
PNU 100766
U 100766
Zyvox
Linospan
Linox
N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide
Zyvoxid
Linezolid-13C-d3
[Molecular Formula]

C16H20FN3O4
[MDL Number]

MFCD00937825
[Molecular Weight]

337.35
[MOL File]

165800-03-3.mol
Chemical PropertiesBack Directory
[Appearance]

White Solid
[mp ]

176-1780C
[Usage]

Prototype of the oxazolidinone antimicrobials; inhibits bacterial mRNA translation.
[CAS DataBase Reference]

165800-03-3(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S36:Wear suitable protective clothing .
[HS Code ]

29349900
[Hazardous Substances Data]

165800-03-3(Hazardous Substances Data)
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Linezolid(165800-03-3).msds
Questions And AnswerBack Directory
[Outline]

Linezolid (U-100766, PNU-100766) developed and produced by the US Pharmacia & Upiohn company (which has been acquired by Pfizer) ,is a new type of azole oxazolidinone class of synthetic antibacterial drugs, the FDA on April 18, 2000 approved the drug to market. This product is the first drug in American in 40 years which is approved for the treatment of methicillin-resistant Staphylococcus aureus infection, September 2007 month in China's listed, it belongs to the Medicare B drugs.
[Indications]

For the treatment of Gram-positive (G +) bacteria caused infections, including concurrent bacteremia; nosocomial pneumonia; community-acquired pneumonia ( because bacteria are not the same,pneumonia is clinically divided into hospital-acquired pneumonia and community-acquired pneumonia) and concomitant bacteremia; it can be applied for the complexity of the skin and skin and soft tissue infections, including osteomyelitis in diabetic foot infections; uncomplicated skin and skin and soft tissue infections; it is also used for the treatment of vancomycin-resistant feces enterococci.
The above information is edited by the chemicalbook of Tian Ye.
[Uses]

fully synthetic oxazolidinone antibiotics.
oxazolidinone antibacterial drugs.
anti-inflammatory drug.
inhibit bacterial mRNA translation.
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