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1660-94-2

1660-94-2 Structure

1660-94-2 Structure
IdentificationMore
[Name]

TETRAETHYL METHYLENEDIPHOSPHONATE
[CAS]

1660-94-2
[Synonyms]

AURORA KA-1506
BIS(DIETHOXYPHOSPHINYL)METHANE
METHYLENEDIPHOSPHONIC ACID TETRAETHYL ESTER
TETRAETHYL(METHYLENE)BISPHOSPHONATE
TETRAETHYL METHYLENEDIPHOSPHONATE
methylenebis(diethylphosphonate)
methylenebis-phosphonicacitetraethylester
methylenedi-phosphonicacitetraethylester
Tetraethyl methylenediphosphonate, 98+%
methanediyl-bis-phosphonic acid tetraethyl ester
Tetraethyl(methylene)bisphosphonate, 98 %
tetraethyl methylenediphosphate
Bis(diethoxyphosphinyl)methane, Methylenediphosphonic acid tetraethylester
[α,β-Methylene]diphosphoric acid tetraethyl
Methylenebis(phosphonic acid diethyl)
Methylenebisphosphonic acid tetraethyl
Methylenedi(phosphonic acid diethyl) ester
[EINECS(EC#)]

216-764-5
[Molecular Formula]

C9H22O6P2
[MDL Number]

MFCD00039887
[Molecular Weight]

288.21
[MOL File]

1660-94-2.mol
Chemical PropertiesBack Directory
[Appearance]

clear yellow to yellow-brown liquid
[Boiling point ]

171-174 °C11 mm Hg(lit.)
[density ]

1.16 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.442(lit.)
[Fp ]

>230 °F
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

Chloroform (Sparingly), Methanol (Slightly)
[form ]

Liquid
[color ]

Clear yellow to yellow-brown
[Specific Gravity]

1.160
[Water Solubility ]

Slightly miscible with water.
[BRN ]

1813241
[InChI]

InChI=1S/C9H22O6P2/c1-5-12-16(10,13-6-2)9-17(11,14-7-3)15-8-4/h5-9H2,1-4H3
[InChIKey]

STJWVOQLJPNAQL-UHFFFAOYSA-N
[SMILES]

C(P(=O)(OCC)OCC)P(=O)(OCC)OCC
[CAS DataBase Reference]

1660-94-2(CAS DataBase Reference)
[EPA Substance Registry System]

Phosphonic acid, methylenebis-, tetraethyl ester (1660-94-2)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P280g-P305+P351+P338
[Hazard Codes ]

Xi,C
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[RTECS ]

SZ9150000
[Hazard Note ]

Corrosive
[TSCA ]

Yes
[HS Code ]

29319090
[Storage Class]

10 - Combustible liquids
[Toxicity]

mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03139,
Hazard InformationBack Directory
[Chemical Properties]

clear yellow to yellow-brown liquid
[Uses]

Tetraethyl methylidenebisphosphonate, can be used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters as potent anti-inflammatory agents. It is also an intermediate for the synthesis of new bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity.
[Synthesis Reference(s)]

Synthetic Communications, 20, p. 1865, 1990 DOI: 10.1080/00397919008053112
Tetrahedron Letters, 34, p. 1515, 1993 DOI: 10.1016/S0040-4039(00)60333-7
[reaction suitability]

reaction type: C-C Bond Formation
Spectrum DetailBack Directory
[Spectrum Detail]

TETRAETHYL METHYLENEDIPHOSPHONATE(1660-94-2)1HNMR
TETRAETHYL METHYLENEDIPHOSPHONATE(1660-94-2)Raman
TETRAETHYL METHYLENEDIPHOSPHONATE(1660-94-2)IR
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Tetraethyl methylenediphosphonate, 97%(1660-94-2)
[Alfa Aesar]

Tetraethyl methylenediphosphonate, 98+%(1660-94-2)
[Sigma Aldrich]

1660-94-2(sigmaaldrich)
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