ChemicalBook--->CAS DataBase List--->16629-19-9

16629-19-9

16629-19-9 Structure

16629-19-9 Structure
IdentificationMore
[Name]

2-Thiophenesulfonyl chloride
[CAS]

16629-19-9
[Synonyms]

2-THIENYLSULFONYL CHLORIDE
2-THIOPHENESULFONYL CHLORIDE
2-THIOPHENESULPHONYL CHLORIDE
AKOS B019397
ART-CHEM-BB B019397
LABOTEST-BB LT00112344
OTAVA-BB BB7020430954
THIOPHENE-2-SULFONYL CHLORIDE
THIOPHENE-2-SULPHONYL CHLORIDE
THIOPHENESULFONYL CHLORIDE
TIMTEC-BB SBB003729
2-(Chlorosulfonyl)-thiophene
2-Thiophene Sulfonylcloride
2-Thienylsulfonyl
2-THIOPHENESULFONYLCHLORIDE,96%
2-Thiophenesulfonic acid chloride
Thiophene-2-sulfonic acid chloride
[EINECS(EC#)]

240-677-1
[Molecular Formula]

C4H3ClO2S2
[MDL Number]

MFCD00005426
[Molecular Weight]

182.65
[MOL File]

16629-19-9.mol
Chemical PropertiesBack Directory
[Appearance]

colorless to brown low melting solid or liquid
[Melting point ]

30-32 °C(lit.)
[Boiling point ]

130-132 °C14 mm Hg(lit.)
[density ]

1.534 (estimate)
[refractive index ]

1.5722-1.5742
[Fp ]

>110°C
[storage temp. ]

2-8°C
[solubility ]

soluble in Chloroform, Ethyl Acetate
[form ]

solid
[color ]

White to Almost white
[Water Solubility ]

Reacts with water.
[Sensitive ]

Moisture Sensitive
[BRN ]

123536
[Stability:]

Moisture sensitive
[InChI]

1S/C4H3ClO2S2/c5-9(6,7)4-2-1-3-8-4/h1-3H
[InChIKey]

VNNLHYZDXIBHKZ-UHFFFAOYSA-N
[SMILES]

ClS(=O)(=O)c1cccs1
[CAS DataBase Reference]

16629-19-9(CAS DataBase Reference)
[NIST Chemistry Reference]

2-Thiophene sulfonyl chloride(16629-19-9)
[EPA Substance Registry System]

16629-19-9(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

C
[Risk Statements ]

R34:Causes burns.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S25:Avoid contact with eyes .
S27:Take off immediately all contaminated clothing .
[RIDADR ]

UN 3261 8/PG 2
[WGK Germany ]

3
[F ]

10-21
[Hazard Note ]

Corrosive
[TSCA ]

T
[HazardClass ]

8
[PackingGroup ]

II
[HS Code ]

29349990
[Storage Class]

8A - Combustible corrosive hazardous materials
[Hazard Classifications]

Skin Corr. 1B
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Chloroform-->Sodium sulfate-->Carbon tetrachloride-->Carbon dioxide-->Chlorosulfonic acid-->Thiophene-->5-iodothiophene-2-sulfonyl chloride-->2-Thiophenesulfonic acid-->2-(Tributylstannyl)thiophene-->Thiophene(SIV) (9CI)-->2-Iodothiophene
[Preparation Products]

2-Thiophenethiol-->1-(Thiophene-2-sulfonyl)-piperidine-3-carboxylic acid-->(Thiophene-2-sulfonylamino)-acetic acid-->tert-Butyl 4-(thiophen-2-ylsulfonyl)piperazine-1-carboxylate-->SR3335
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Thiophene-2-sulfonyl chloride(16629-19-9).msds
Hazard InformationBack Directory
[Chemical Properties]

2-Thiophenesulfonyl chloride is colorless to brown low melting solid or liquid
[Uses]

2-Thiophenesulfonyl chloride is a compound used in the preparation of various pharmaceuticals. Thiophene-2-sulfonyl Chloride was used as an intermediate in the synthesis of β-Cell apoptosis supressor .
[Synthesis Reference(s)]

The Journal of Organic Chemistry, 39, p. 3286, 1974 DOI: 10.1021/jo00936a030
[General Description]

Kinetics of reactions of 2-thiophenesulfonyl chloride with substituted anilines in methanol has been reported. Kinetics of solvolysis of 2-thiophenesulfonyl chloride in binary solvent mixtures has been studied.
Spectrum DetailBack Directory
[Spectrum Detail]

2-Thiophenesulfonyl chloride(16629-19-9)1HNMR
2-Thiophenesulfonyl chloride(16629-19-9)13CNMR
2-Thiophenesulfonyl chloride(16629-19-9)IR
2-Thiophenesulfonyl chloride(16629-19-9)FT-IR
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

2-Thiophenesulfonyl chloride, 98%(16629-19-9)
[Alfa Aesar]

Thiophene-2-sulfonyl chloride, 97%(16629-19-9)
[Sigma Aldrich]

16629-19-9(sigmaaldrich)
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