ChemicalBook--->CAS DataBase List--->16874-12-7

16874-12-7

16874-12-7 Structure

16874-12-7 Structure
IdentificationMore
[Name]

tert-Butyl L-tyrosinate
[CAS]

16874-12-7
[Synonyms]

H-TYR-OBUT
H-TYR-OTBU
L-TYROSINE T-BUTYL ESTER
L-TYROSINE TERT-BUTYL ESTER
tert-butyl l-tyrosinate
TYROSINE-OTBU
2-Amino-3-(4-hydroxy-phenyl)-propionic acid tert-butyl ester
Tyr-OtBu
L-TYROSINE TERT-BUTYL ESTER 98+%
H-Tyr-OBu
H-L-Tyr-OtBu
(2S)-2-Amino-3-(4-hydroxyphenyl)propanoic acid tert-butyl ester
L-Tyrosine 1,1-dimethylethyl ester
Tyrosine tert-butyl ester
[EINECS(EC#)]

240-902-3
[Molecular Formula]

C13H19NO3
[MDL Number]

MFCD00042644
[Molecular Weight]

237.29
[MOL File]

16874-12-7.mol
Chemical PropertiesBack Directory
[Appearance]

Crystalline
[Melting point ]

141-144 °C
[Boiling point ]

358.1±27.0 °C(Predicted)
[density ]

1.125±0.06 g/cm3(Predicted)
[refractive index ]

25 ° (C=2, EtOH)
[storage temp. ]

2-8°C
[solubility ]

soluble in Methanol
[form ]

Powder
[pka]

9.80±0.15(Predicted)
[color ]

White
[Optical Rotation]

[α]20/D +25±1°, c = 2% in ethanol
[BRN ]

2696011
[Major Application]

peptide synthesis
[InChI]

InChI=1S/C13H19NO3/c1-13(2,3)17-12(16)11(14)8-9-4-6-10(15)7-5-9/h4-7,11,15H,8,14H2,1-3H3/t11-/m0/s1
[InChIKey]

DIGHFXIWRPMGSA-NSHDSACASA-N
[SMILES]

C(OC(C)(C)C)(=O)[C@H](CC1=CC=C(O)C=C1)N
[CAS DataBase Reference]

16874-12-7(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
GHS07,GHS08,GHS09
[Signal word ]

Danger
[Hazard statements ]

H302-H361-H372-H410
[Precautionary statements ]

P201-P264-P280-P301+P330+P331-P312
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[HS Code ]

29225090
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

Crystalline
[Uses]

L-Tyrosine tert-butyl ester is a protected form of L-Tyrosine (T899975). L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines (e.g. Norepinephrine HCl [N674500]) in human keratinocytes, and also for the synthesis of proteins and thyroid hormones.
[reaction suitability]

reaction type: solution phase peptide synthesis
[Synthesis]

To a solution of tert-butyl (S)-4-benzyloxyphenylalaninate (65.5 mg, 0.2 mmol) in tetrahydrofuran (2 mL) was added palladium (10 mg) on 10% activated charcoal at zero degrees Celsius under an argon atmosphere, then the reaction system was bubbled with H2
Spectrum DetailBack Directory
[Spectrum Detail]

tert-Butyl L-tyrosinate(16874-12-7)MS
tert-Butyl L-tyrosinate(16874-12-7)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

16874-12-7(sigmaaldrich)
[TCI AMERICA]

L-Tyrosine tert-Butyl Ester,>97.0%(LC)(T)(16874-12-7)
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