| Identification | More | [Name]
tert-Butyl L-tyrosinate | [CAS]
16874-12-7 | [Synonyms]
H-TYR-OBUT
H-TYR-OTBU
L-TYROSINE T-BUTYL ESTER
L-TYROSINE TERT-BUTYL ESTER
tert-butyl l-tyrosinate
TYROSINE-OTBU
2-Amino-3-(4-hydroxy-phenyl)-propionic acid tert-butyl ester
Tyr-OtBu
L-TYROSINE TERT-BUTYL ESTER 98+%
H-Tyr-OBu
H-L-Tyr-OtBu
(2S)-2-Amino-3-(4-hydroxyphenyl)propanoic acid tert-butyl ester
L-Tyrosine 1,1-dimethylethyl ester
Tyrosine tert-butyl ester | [EINECS(EC#)]
240-902-3 | [Molecular Formula]
C13H19NO3 | [MDL Number]
MFCD00042644 | [Molecular Weight]
237.29 | [MOL File]
16874-12-7.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline | [Melting point ]
141-144 °C | [Boiling point ]
358.1±27.0 °C(Predicted) | [density ]
1.125±0.06 g/cm3(Predicted) | [refractive index ]
25 ° (C=2, EtOH) | [storage temp. ]
2-8°C
| [solubility ]
soluble in Methanol | [form ]
Powder | [pka]
9.80±0.15(Predicted) | [color ]
White | [Optical Rotation]
[α]20/D +25±1°, c = 2% in ethanol | [BRN ]
2696011 | [InChI]
InChI=1S/C13H19NO3/c1-13(2,3)17-12(16)11(14)8-9-4-6-10(15)7-5-9/h4-7,11,15H,8,14H2,1-3H3/t11-/m0/s1 | [InChIKey]
DIGHFXIWRPMGSA-NSHDSACASA-N | [SMILES]
C(OC(C)(C)C)(=O)[C@H](CC1=CC=C(O)C=C1)N | [CAS DataBase Reference]
16874-12-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29225090 |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline | [Uses]
L-Tyrosine tert-butyl ester is a protected form of L-Tyrosine (T899975). L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines (e.g. Norepinephrine HCl [N674500]) in human keratinocytes, and also for the synthesis of proteins and thyroid hormones. | [reaction suitability]
reaction type: solution phase peptide synthesis | [Synthesis]
To a solution of tert-butyl (S)-4-benzyloxyphenylalaninate (65.5 mg, 0.2 mmol) in tetrahydrofuran (2 mL) was added palladium (10 mg) on 10% activated charcoal at zero degrees Celsius under an argon atmosphere, then the reaction system was bubbled with H2 |
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