| Identification | More | [Name]
4-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE | [CAS]
1701-24-2 | [Synonyms]
4-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE
BUTTPARK 29\04-05
4-Chloro-2-(trifluoromethyl)quinoline 97%
4-Chloro-2-(trifluoromethyl)quinoline97% | [Molecular Formula]
C10H5ClF3N | [MDL Number]
MFCD00153105 | [Molecular Weight]
231.6 | [MOL File]
1701-24-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
34-38 °C | [Boiling point ]
236.4±35.0 °C(Predicted) | [density ]
1.427±0.06 g/cm3(Predicted) | [Fp ]
225°C | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
powder to lump to clear liquid | [pka]
-1.19±0.50(Predicted) | [color ]
White or Colorless to Almost white or Almost colorless | [InChI]
1S/C10H5ClF3N/c11-7-5-9(10(12,13)14)15-8-4-2-1-3-6(7)8/h1-5H | [InChIKey]
ONNDFDQMHCNEGF-UHFFFAOYSA-N | [SMILES]
FC(F)(F)c1cc(Cl)c2ccccc2n1 | [CAS DataBase Reference]
1701-24-2(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Uses]
4-Chloro-2-(trifluoromethyl)quinoline is a pharmaceutical intermediate that can be used to prepare N-(4-nitrophenylethyl)-2-(trifluoromethyl)quinoline-4-amine, a STAT3 inhibitor. |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2933499090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Synthesis]
4-Chloro-2-(trifluoromethyl)quinoline (100.0 mg, 0.43 mmol), 2-(4-nitrophenyl)ethan-1-amine hydrochloride (87.0 mg, 0.43 mmol) and Et3N (180.0 μL, 1.29 mmol) were added to NMP (1.0 mL). The reaction mixture was allowed to react in a microwave oven (50 W, |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
|