| Identification | Back Directory | [Name]
CP 316311 | [CAS]
175139-41-0 | [Synonyms]
CP 316311
Pyridine, 4-(1-ethylpropoxy)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)- | [Molecular Formula]
C21H29NO2 | [MDL Number]
MFCD09965892 | [MOL File]
175139-41-0.mol | [Molecular Weight]
327.46 |
| Chemical Properties | Back Directory | [Melting point ]
72.5-74 °C | [Boiling point ]
413.9±40.0 °C(Predicted) | [density ]
1.007±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
5.63±0.30(Predicted) |
| Hazard Information | Back Directory | [Biological Activity]
CP 316311 is a potent and selective CRF1 receptor antagonist with IC50 of 6.8 nM. | [in vitro]
CP 316311 fully antagonizes CRF-stimulated adenylate cyclase activity in rat cortex and at human CRF1 receptors endogenously expressed in IMR32 cells with apparent K i values of 7.6 and 8.5 nM, respectively. < /p> | [target]
IC50: 6.8 nM (CRF1 receptor) | [storage]
Store at -20°C |
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